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REVIEW article

Front. Neurosci.

Sec. Neuroscience Methods and Techniques

Volume 19 - 2025 | doi: 10.3389/fnins.2025.1591605

This article is part of the Research TopicIntegrating Multimodal Approaches to Unravel Neural Mechanisms of Learning and CognitionView all 6 articles

The Application Of Radiomics In The Diagnosis And Evaluation Of Cognitive Impairment Related To Neurological Diseases

Provisionally accepted
Haixing  XiaoHaixing Xiao1Xinyi  HeXinyi He1Wei  ZhouWei Zhou1Xianghong  GuoXianghong Guo2Xiuying  CaiXiuying Cai1*Tan  LiTan Li1*
  • 1The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China
  • 2Suzhou Industrial Park Xinghai Hospital, Suzhou, China

The final, formatted version of the article will be published soon.

Cognitive impairment (CI) is common, with diverse underlying causes, symptoms, and imaging features. It often leads to disability and loss of independence. Early diagnosis and assessment of CI are crucial for the prognosis improvement. Conventional diagnostic methods for CI are hindered by subjectivity and imprecision. Radiomics, a sophisticated and objective methodology, has been increasingly utilized in CI in recent times. This article describes the methodology of radiomics and reviews the application of radiomics in the prediction and evaluation of cognitive impairment related to neurological diseases such as Alzheimer's disease (AD), Parkinson ' s disease (PD), Cerebral small vessel disease (CSVD), and Stroke. It can provide imaging markers for the early diagnosis and risk stratification of cognitive impairment.

Keywords: cognitive impairment, Radiomics, Alzheimer's disease, Parkinson's disease, Cerebral small vessel disease, Stroke

Received: 11 Mar 2025; Accepted: 19 Jun 2025.

Copyright: © 2025 Xiao, He, Zhou, Guo, Cai and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Xiuying Cai, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China
Tan Li, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China

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