REVIEW article
Front. Neurosci.
Sec. Brain Imaging Methods
Volume 19 - 2025 | doi: 10.3389/fnins.2025.1596459
This article is part of the Research TopicUnraveling Cognitive Impairment: A Multimodal MRI Approach to Brain NetworksView all 10 articles
Advances in the use of structural and diffusion magnetic resonance imaging for characterizing SCD and MCI due to Alzheimer's disease
Provisionally accepted
- 1Gansu University of Chinese Medicine, Lanzhou, China
- 2The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou, Gansu, China
- 3The Second Affiliated Hospital of Army Military Medical University, Chongqing, China
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Alzheimer's disease (AD) has become a great concern for society in general and clinicians specifically because of its high morbidity, relative lack of awareness of its characteristics, and low diagnosis and treatment rates. Worldwide, there is a lack of effective treatments for slowing the progression of AD in clinical practice. Thus, the management of patients in the preclinical phase of AD (PPAD) has been identified to be highly important for addressing this concern. PPAD is considered a preclinical manifestation of the early stages of AD and includes subjective cognitive decline (SCD) and mild cognitive impairment (MCI). Developments in magnetic resonance imaging (MRI) technology have led to its demonstration of great potential in the early identification and progression monitoring of PPAD.
Keywords: Subjective cognitive decline, Mild Cognitive Impairment, structural magnetic resonance imaging, sMRI, Diffusion Tensor Imaging, DTI
Received: 19 Mar 2025; Accepted: 30 Jul 2025.
Copyright: © 2025 Yang, Dong, Zhao, Liu, Cai, Bian and Ding. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shi-Zhu Bian, The Second Affiliated Hospital of Army Military Medical University, Chongqing, China
Xiao-Han Ding, Gansu University of Chinese Medicine, Lanzhou, China
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