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CORRECTION article

Front. Neurosci., 01 September 2025

Sec. Neurodevelopment

Volume 19 - 2025 | https://doi.org/10.3389/fnins.2025.1684866

Correction: Trajectories of working memory and decision making abilities along juvenile development in mice

  • Institute of Developmental Neurophysiology, Center for Molecular Neurobiology, Hamburg Center of Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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In the published article, there was an error in Figure 4 as published. Two images were wrongly used in Figure 4. Figure 4D (OFC right) is same as in Figure 4D (OFC middle). Figure 4D (dSTr middle) is same as in Figure 4D (S1 left). The corrected Figure 4 and its caption appear below.

Figure 4

Diagram showing a study of neuronal activity in mice using cFos immunohistochemistry. Panel A illustrates the experimental timeline and methodology, including mouse age groups P24, P35, and P60, with image acquisition process. Panels B and C display brain sections with cFos and DAPI staining, highlighting regions like M2, Cg, PL, and vHP. Panel D compares cFos across age groups in different brain regions such as frontal, subcortical, and sensory-motor areas. Panels E and F depict heatmaps of cell counts and z-scored cell numbers. Panel G shows a p-value heatmap indicating significance across age groups.

Brain-wide basal cFos expression along mouse development. (A) Flow chart displaying the experimental design of immunohistochemistry staining of brain slices against cFos, confocal image acquisition, and Cellpose image quantification. (B) Left, representative confocal images of DAPI (blue) and cFos (red) stainings (left) as well as color-coded schematic reference images from the Allen brain atlas illustrating the brain regions of interest (right, M2, Cg, PL, IL, OFC) of atlas section 37. Right, same as left for atlas section 44 including CLA, dSTR, vSTR. (C) Same as (B) for atlas section 74 including S1, dHP, MD (left) and for atlas section 87 including V1, vHP, EC (right). (D) Representative confocal images of cFos expression in frontal, subcortical, hippocampal, and sensory-motor areas from Pre, Juv, and Adu mice. (E) Color-coded heatmap of the number of cFos positive cells for each investigated brain area for Pre (n = 332 images, 4 mice), Juv (n = 384 images, 4 mice), and Adu (n = 323 images, 4 mice) mice. Data are presented as mean per brain area. (F) Same as (E) for row z-scored number of cFos positive cells. (G) Color-coded heatmap of statistical results of age group effects for each investigated brain area. Statistics were performed with LME models (# cells ~ age group * brain area + (1 | animal) + (1 | slice) + (1 | sex)). See also Statistics table S1 for detailed statistics.

The original version of this article has been updated.

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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

working memory, decision making, mouse behavior, development, prefrontal cortex, cFos

Citation

Thies AM, Pochinok I, Marquardt A, Dorofeikova M, Hanganu-Opatz IL and Pöpplau JA (2025) Correction: Trajectories of working memory and decision making abilities along juvenile development in mice. Front. Neurosci. 19:1684866. doi: 10.3389/fnins.2025.1684866

Received

13 August 2025

Accepted

20 August 2025

Published

01 September 2025

Volume

19 - 2025

Edited and reviewed by

Paola Tognini, Sant'Anna School of Advanced Studies, Italy

Updates

Copyright

*Correspondence: Jastyn A. Pöpplau

†These authors share last authorship

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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