ORIGINAL RESEARCH article
Front. Neurosci.
Sec. Neural Technology
The effects of transcranial direct current stimulation on EEG power and complexity of ischemic stroke
Provisionally accepted- The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, Shijiazhuang, Hebei, China
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Transcranial direct current stimulation (tDCS), has shown therapeutic potential for ischemic stroke, but the neural oscillatory mechanisms of its therapeutic effects remain incompletely elucidated. Based on the rat model and clinical stroke patients, this paper combines multiple indicators such as electroencephalography (EEG) relative power (RP), Lempel-Ziv complexity and sample entropy to investigate the mechanism by which tDCS modulates neural oscillations in ischemic stroke. The results indicated that tDCS substantially reduced the RP of the δ frequency band, enhanced the normal oscillation of the α frequency band, and improved the complexity index of the EEG signals. These findings suggest that tDCS could facilitate the recovery following ischemic stroke through the modulation of EEG rhythms.
Keywords: transcranial direct current stimulation, ischemic stroke, Neural oscillations, relative power, Lempel-Ziv complexity, sample entropy
Received: 18 Aug 2025; Accepted: 27 Nov 2025.
Copyright: © 2025 Xi, Song, Ma and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Wang Xi
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
