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ORIGINAL RESEARCH article

Front. Neurosci.

Sec. Neural Technology

The effects of transcranial direct current stimulation on EEG power and complexity of ischemic stroke

Provisionally accepted
Wang  XiWang Xi*Guoqiang  SongGuoqiang SongZhizhao  MaZhizhao MaLiqiang  LiuLiqiang Liu
  • The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, Shijiazhuang, Hebei, China

The final, formatted version of the article will be published soon.

Transcranial direct current stimulation (tDCS), has shown therapeutic potential for ischemic stroke, but the neural oscillatory mechanisms of its therapeutic effects remain incompletely elucidated. Based on the rat model and clinical stroke patients, this paper combines multiple indicators such as electroencephalography (EEG) relative power (RP), Lempel-Ziv complexity and sample entropy to investigate the mechanism by which tDCS modulates neural oscillations in ischemic stroke. The results indicated that tDCS substantially reduced the RP of the δ frequency band, enhanced the normal oscillation of the α frequency band, and improved the complexity index of the EEG signals. These findings suggest that tDCS could facilitate the recovery following ischemic stroke through the modulation of EEG rhythms.

Keywords: transcranial direct current stimulation, ischemic stroke, Neural oscillations, relative power, Lempel-Ziv complexity, sample entropy

Received: 18 Aug 2025; Accepted: 27 Nov 2025.

Copyright: © 2025 Xi, Song, Ma and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Wang Xi

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