Frontiers in Physiology | Respiratory Physiology and Pathophysiology

Original Research

Published on 19 Dec 2025

Increased work of breathing and its relationship to dyspnea in malignant pleural effusion

in Respiratory Physiology and Pathophysiology

Tomasz Gólczewski
Anna M. Stecka
Elżbieta M. Grabczak
Monika Zielińska-Krawczyk
Rafał Krenke

Frontiers in Physiology

doi 10.3389/fphys.2025.1664237

264 views

Original Research

Published on 18 Dec 2025

Prognostic value of the relative neutrophil–monocyte-to-lymphocyte–albumin ratio in chronic lower respiratory diseases: a multicenter retrospective analysis

in Respiratory Physiology and Pathophysiology

Xu Chen
Yi Zhang
Xueyuan Wang
Liping Ye
Kaijia Shi
Xinghan Tian

Frontiers in Physiology

doi 10.3389/fphys.2025.1708302

393 views

Case Report

Accepted on 17 Dec 2025

Re-ascent Triggered High Altitude Pulmonary and Cerebral Edema in a Tibetan with Pre-existing High-Altitude Polycythemia: A Case Report

in Respiratory Physiology and Pathophysiology

He Huang
Shuaijun Yuan
Limin Zhang
Jiaye Song
Dengwei Xue
Dongmei Liu
Jingxin Cao

Frontiers in Physiology

Review

Accepted on 16 Dec 2025

Bedside Detection and Monitoring of Pulmonary Embolism Using Electrical Impedance Tomography

in Respiratory Physiology and Pathophysiology

Mingyuan Deng
Nianze Li
Jiafeng Wang
Mingjing Yu

Frontiers in Physiology

Original Research

Accepted on 08 Dec 2025

The dose-effect and clinical prediction of the longest apnea duration driving the decrease of blood oxygen: A large sample OSA study with 34-second and 52-second cut-off values was established

in Respiratory Physiology and Pathophysiology

Xiaobo Zhou
Simin Gao
Ping Zeng
Lin Li

Frontiers in Physiology

Brief Research Report

Published on 03 Dec 2025

Hemoglobin mass does not increase in able-bodied individuals after consecutive days of acute intermittent hypoxia

in Respiratory Physiology and Pathophysiology

Andrew S. Harding
Katelyn D. Noyes
Aviva K. Pollet
Sewan Kim
Andrew Q. Tan

Frontiers in Physiology

doi 10.3389/fphys.2025.1714165

520 views

Original Research

Published on 01 Dec 2025

Effects of resistance exercise training on oxygen consumption and minute by minute efficiency during the six-minute walk test in female breast cancer survivors

in Respiratory Physiology and Pathophysiology

Rodrigo Muñoz-Cofre
Macarena Artigas-Arias
Fernando Valenzuela-Aedo
Máximo Escobar-Cabello
Mariano del Sol
Daniel Conei
Jorge Sapunar
Rui Curi
Gabriel Nasri Marzuca-Nassr

Frontiers in Physiology

doi 10.3389/fphys.2025.1694076

525 views

Original Research

Published on 01 Dec 2025

Impact of individualized tidal volume strategies on intraoperative lung protection and inflammatory markers in laparoscopic cholecystectomy: a randomized controlled trial

in Respiratory Physiology and Pathophysiology

Xin Wang
Wei Hao
Li-Fang Wu

Frontiers in Physiology

doi 10.3389/fphys.2025.1667207

605 views

Original Research

Published on 26 Nov 2025

Computationally-directed mechanical ventilation in a porcine model of ARDS

in Respiratory Physiology and Pathophysiology

Michaela Kollisch-Singule
Andrea F. Cruz
Jacob Herrmann
Joshua Satalin
Sarah Satalin
Brian P. Harvey
Dorian LeCroy
George Beck
Mark Lutz
Jacob Charlamb

Frontiers in Physiology

doi 10.3389/fphys.2025.1602578

880 views

Original Research

Published on 24 Nov 2025

Interrogating pulmonary diffusing capacity in long COVID: insights from DLCO and DLNO testing

in Respiratory Physiology and Pathophysiology

Jordan K. Parks
Bruce D. Johnson
Meredith G. Shea
Chul-Ho Kim
Jessica I. Johnston
Alex Carlson
Jesse C. Schwartz
Courtney M. Wheatley-Guy

Frontiers in Physiology

doi 10.3389/fphys.2025.1725263

864 views

Editorial

Published on 24 Nov 2025

Editorial: Translating biomechanics of the human airways for classification, diagnosis and treatment of pulmonary diseases

in Respiratory Physiology and Pathophysiology

Aranyak Chakravarty
Saikat Basu
Mahesh V. Panchagnula
Neelesh A. Patankar

Frontiers in Physiology

doi 10.3389/fphys.2025.1743792

615 views

Systematic Review

Accepted on 20 Nov 2025

Effect of Hemodialysis in End-Stage Renal disease patients on Pulmonary Function Tests: A Meta-Analysis of Cross-sectional Studies

in Respiratory Physiology and Pathophysiology

Qing Zhang
Youyou Xu
Dan Huang
Jiaru Jiang
Sicong Jiang
Huichao Wu

Frontiers in Physiology

175 views

Original Research

Published on 17 Nov 2025

Surgical hyoid bone repositioning effects on mandibular advancement and upper airway collapsibility: an anesthetized rabbit model study

in Respiratory Physiology and Pathophysiology

Hiba J. Tannous
Corine J. Samaha
Hassan A. Chami
Joseph G. Ghafari
Jason Amatoury

Frontiers in Physiology

doi 10.3389/fphys.2025.1618037

737 views

Original Research

Published on 17 Nov 2025

Associations between body mass index and lung function using Z-scores: a nonlinear relationship and machine learning classification modeling

in Respiratory Physiology and Pathophysiology

Wei Feng
Fei Lu
Jiangjiang Liu
Yu Zhang
Shiyu Shen
Haitao Ma

Frontiers in Physiology

doi 10.3389/fphys.2025.1706759

842 views

Original Research

Published on 11 Nov 2025

Sequencing and bioinformatics analysis of exosome-derived miRNAs in mouse models of pancreatic injury induced by OSA

in Respiratory Physiology and Pathophysiology

Jiuhuang Lan
Jiayi Lin
Yaopeng Guo
Meilin Ji
Yizhao Lin
Qingshi Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1712442

603 views

Original Research

Published on 05 Nov 2025

Mitophagy-associated biomarkers and macrophage involvement in pulmonary arterial hypertension: identification and functional implications

in Respiratory Physiology and Pathophysiology

Xiaoyu Zhang
Liming Cheng
Jiahui Xie
Xuejuan Ma
Wenting Gui
Jiaxiang Chen
Kai Liu
Runwei Ma

Frontiers in Physiology

doi 10.3389/fphys.2025.1673181

1,751 views

Original Research

Published on 20 Oct 2025

Diagnostic predictive evaluation of pneumocystis jirovecii pneumonia using digital chest CT analysis combined with clinical features

in Respiratory Physiology and Pathophysiology

Yunfeng Chen
Xiaodie Xu
Zhigui Huang
Xiuting Lai
Chuzhao Li
Jingyi Chen
Weijing Wu
Kavimbi Chipusu
Yiming Zeng

Frontiers in Physiology

doi 10.3389/fphys.2025.1616791

1,471 views

Review

Published on 16 Oct 2025

Mechanisms of alveolar type II epithelial cells’ mitochondrial quality control during acute lung injury/acute respiratory distress syndrome: bridging the gap between oxidative stress, inflammation, and fibrosis

in Respiratory Physiology and Pathophysiology

Lin Zeng
Jiangtian Yan

Frontiers in Physiology

doi 10.3389/fphys.2025.1684729

2,007 views

Review

Published on 15 Oct 2025

Insulin-like growth factor family and its impact on pulmonary arterial hypertension: a review

in Respiratory Physiology and Pathophysiology

Nuo Li
Degang Mo
Hongyan Dai

Frontiers in Physiology

doi 10.3389/fphys.2025.1679278

1,621 views

Original Research

Published on 03 Oct 2025

YAP activity protects against ventilator-induced lung injury

in Respiratory Physiology and Pathophysiology

Huan Liu
Xuepeng Yang
Feng Qi
Xuan Li
Yu Liu
Ge Liu
Xiaojie Lin

Frontiers in Physiology

doi 10.3389/fphys.2025.1578901

1,931 views

Original Research

Published on 01 Oct 2025

The impact of obesity on upper airway anatomy as assessed by magnetic resonance imaging and obstructive sleep apnea endotypic traits

in Respiratory Physiology and Pathophysiology

Brandon Nokes
Aaron Schueler
Chantal Darquenne
Cristopher N. Schmickl
Brian S. Wojeck
Stacie Moore
Pamela Deyoung
Lana McGinnis
Rebecca J. Theilmann
Eli Gruenberg

Frontiers in Physiology

doi 10.3389/fphys.2025.1648767

2,033 views

Original Research

Published on 26 Sep 2025

Between endothelial activation and stress index (EASIX) and mortality in acute respiratory distress syndrome (ARDS) patients: a multicenter retrospective study

in Respiratory Physiology and Pathophysiology

Juan Chen
Jing Lv
Meijun Liu
Xue Dai
Wang Deng

Frontiers in Physiology

doi 10.3389/fphys.2025.1570988

2,098 views

Original Research

Published on 24 Sep 2025

Effects of oral, oronasal, and oronasal breathing with a decongested nose during incremental maximal exercise testing of well-trained endurance athletes: a randomized cross-over study

in Respiratory Physiology and Pathophysiology

J. Bergqvist
F. Reite
F. Edin
L. Schiöler
M. Börjesson
S. Steinsvåg
S. Pettersson
J. Hellgren

Frontiers in Physiology

doi 10.3389/fphys.2025.1654725

2,236 views

Methods

Published on 24 Sep 2025

Perspectives on physics-based one-dimensional modeling of lung physiology

in Respiratory Physiology and Pathophysiology

Aranyak Chakravarty
Debjit Kundu
Mahesh V. Panchagnula
Alladi Mohan
Neelesh A. Patankar

Frontiers in Physiology

doi 10.3389/fphys.2025.1635983

1,857 views
1 citation

639 articles

articles

Increased work of breathing and its relationship to dyspnea in malignant pleural effusion

Prognostic value of the relative neutrophil–monocyte-to-lymphocyte–albumin ratio in chronic lower respiratory diseases: a multicenter retrospective analysis

Re-ascent Triggered High Altitude Pulmonary and Cerebral Edema in a Tibetan with Pre-existing High-Altitude Polycythemia: A Case Report

Bedside Detection and Monitoring of Pulmonary Embolism Using Electrical Impedance Tomography

The dose-effect and clinical prediction of the longest apnea duration driving the decrease of blood oxygen: A large sample OSA study with 34-second and 52-second cut-off values was established

Hemoglobin mass does not increase in able-bodied individuals after consecutive days of acute intermittent hypoxia

Effects of resistance exercise training on oxygen consumption and minute by minute efficiency during the six-minute walk test in female breast cancer survivors

Impact of individualized tidal volume strategies on intraoperative lung protection and inflammatory markers in laparoscopic cholecystectomy: a randomized controlled trial

Computationally-directed mechanical ventilation in a porcine model of ARDS

Interrogating pulmonary diffusing capacity in long COVID: insights from DLCO and DLNO testing

Editorial: Translating biomechanics of the human airways for classification, diagnosis and treatment of pulmonary diseases

Effect of Hemodialysis in End-Stage Renal disease patients on Pulmonary Function Tests: A Meta-Analysis of Cross-sectional Studies

Surgical hyoid bone repositioning effects on mandibular advancement and upper airway collapsibility: an anesthetized rabbit model study

Associations between body mass index and lung function using Z-scores: a nonlinear relationship and machine learning classification modeling

Sequencing and bioinformatics analysis of exosome-derived miRNAs in mouse models of pancreatic injury induced by OSA

Mitophagy-associated biomarkers and macrophage involvement in pulmonary arterial hypertension: identification and functional implications

Diagnostic predictive evaluation of pneumocystis jirovecii pneumonia using digital chest CT analysis combined with clinical features

Mechanisms of alveolar type II epithelial cells’ mitochondrial quality control during acute lung injury/acute respiratory distress syndrome: bridging the gap between oxidative stress, inflammation, and fibrosis

Insulin-like growth factor family and its impact on pulmonary arterial hypertension: a review

YAP activity protects against ventilator-induced lung injury

The impact of obesity on upper airway anatomy as assessed by magnetic resonance imaging and obstructive sleep apnea endotypic traits

Between endothelial activation and stress index (EASIX) and mortality in acute respiratory distress syndrome (ARDS) patients: a multicenter retrospective study

Effects of oral, oronasal, and oronasal breathing with a decongested nose during incremental maximal exercise testing of well-trained endurance athletes: a randomized cross-over study

Perspectives on physics-based one-dimensional modeling of lung physiology