Frontiers in Physiology | Skeletal Physiology

Original Research

Accepted on 22 Jan 2026

Reliability of DIERS pedogait system for evaluating spatiotemporal gait parameters in knee osteoarthritis and its association with Achilles tendon stiffness asymmetry

in Skeletal Physiology

Xingxing Shen
Jiahao Chen
Jiahao Zhang
Jiaqing Tian
Sirun Cheng
Jichuan Cao
Congcong Li
Xuemeng Xu

Frontiers in Physiology

Systematic Review

Published on 12 Jan 2026

Meta-analysis of comparative effects of mobile app–based digital rehabilitation versus traditional rehabilitation after total knee arthroplasty

in Skeletal Physiology

Liang Ma
Jia-Qiang Liu
Kun Yu
Mei-Yun Tan

Frontiers in Physiology

doi 10.3389/fphys.2025.1737373

577 views

Original Research

Accepted on 31 Dec 2025

Influence of adrenoceptor blocker treatment on fracture healing in osteoporotic and non-osteoporotic bone

in Skeletal Physiology

Sandra Dieterich
Christoph Kölbl
Miriam Eva Angelica Tschaffon-Müller
Oliver Küppers
Dorothea Gebauer
Melanie Rebecca Kuhn
Katarina Teresa Acker
Anita Ignatius
Melanie Haffner-Luntzer

Frontiers in Physiology

238 views

Original Research

Published on 02 Dec 2025

Comparison of quadriceps femoris properties, surface electromyography parameters and foot posture asymmetries between patients with unilateral and bilateral knee osteoarthritis

in Skeletal Physiology

Xingxing Shen
Jiaqing Tian
Jiahao Chen
Jiahao Zhang
Sirun Cheng
Ruian Xiang
Xuemeng Xu

Frontiers in Physiology

doi 10.3389/fphys.2025.1710819

1,058 views

Review

Published on 17 Nov 2025

The role of cell death in the physiological and pathological processes of skeletal muscle

in Skeletal Physiology

Hongyi Xu
Zihui Gao
Xinlei Yao
Jiacheng Sun
Bingqian Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1717233

2,103 views

Review

Published on 04 Nov 2025

Multiple pathways of the actin-myosin cycle in energy transduction and the release of orthophosphate in muscle

in Skeletal Physiology

Marco Caremani
Irene Pertici
Ilaria Morotti
Pasquale Bianco
Massimo Reconditi
Gabriella Piazzesi
Vincenzo Lombardi
Marco Linari

Frontiers in Physiology

doi 10.3389/fphys.2025.1664568

2,764 views

Original Research

Published on 03 Nov 2025

Non-neuronal cholinergic stimulation favors bone mass accrual

in Skeletal Physiology

Faleh Tamimi
Hazem Eimar
Sharifa Alebrahim
Lina Abu-Nada
Garthiga Manickam
Ahmed Ebraheem Al Subaie
Iskandar Tamimi
Monzur Murshed

Frontiers in Physiology

doi 10.3389/fphys.2025.1684102

1,266 views

Perspective

Published on 30 Oct 2025

Meeting report: the inaugural muscle biology and cachexia conference at the University of Houston, May 18-20, 2025, Houston, Texas, USA

in Skeletal Physiology

Jingjuan Chen
Marco Brotto
Radbod Darabi
Ashok Kumar

Frontiers in Physiology

doi 10.3389/fphys.2025.1711795

1,563 views

Review

Published on 29 Oct 2025

Single-cell sequencing reveals cellular heterogeneity and molecular mechanisms in tendon and enthesis injury repair

in Skeletal Physiology

Tingming Pan
Zhong Dong
Hongjie Zhang
Fengmin Yang
Yating Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1685955

1,783 views

Review

Published on 27 Oct 2025

Pathophysiological mechanisms and emerging therapeutic strategies for muscle wasting: an integrative review

in Skeletal Physiology

Jiahao Huang
Tianshan Wen
Huijun Wei
Jiliang Kang
Junyue Lu
Taian Zhou
Youliang Wen
Haoyuan Huang

Frontiers in Physiology

doi 10.3389/fphys.2025.1674892

2,008 views

Original Research

Published on 01 Oct 2025

Characterization of human skeletal stem cells in closed and open tibia fractures: a single center pilot study

in Skeletal Physiology

Rubén Tresgallo-Parés
David Morales
Shannon Tse
Aziz Saade
Ellen Fitzpatrick
Sean T. Campbell
Gillian L. Soles
Thomas H. Ambrosi
Mark A. Lee
Augustine M. Saiz

Frontiers in Physiology

doi 10.3389/fphys.2025.1638064

3,007 views

Original Research

Published on 26 Sep 2025

Identification and functional analysis of circular RNAs in intervertebral disc lesion tissues from spinal tuberculosis patients

in Skeletal Physiology

Linan Wang
Xingyu Duan
Yuliang Qu
Zhiyun Shi
Xu Zhang
Zongqiang Yang
Yingchao Gao
Ningkui Niu

Frontiers in Physiology

doi 10.3389/fphys.2025.1650380

2,619 views

Original Research

Published on 23 Sep 2025

Correlation analysis of osteoporosis and vertebral endplate defects using CT and MRI imaging: a retrospective cross-sectional study

in Skeletal Physiology

Song Hao
Luo Yuxiao
Li Huilan
Hua Jun
Liu Dong

Frontiers in Physiology

doi 10.3389/fphys.2025.1649477

2,332 views
1 citation

Original Research

Published on 04 Sep 2025

Cuproptosis related genes in immune infiltration and treatment of osteoporosis by bioinformatic analysis and machine learning methods

in Skeletal Physiology

Haiyang Wu
Junhao Wu
Guowei Wen

Frontiers in Physiology

doi 10.3389/fphys.2025.1605473

3,061 views

Original Research

Published on 26 Aug 2025

Deep behavioral phenotyping tracks functional recovery following tibia fracture in mice

in Skeletal Physiology

Jonathan E. Layne
Dustin M. Snapper
Molly E. Czachor
Charles Lam
Jacob D. Matityahu
Dane R. G. Lind
Matthieu Huard
Johnny Huard
Kazuhito Morioka
Julian C. Motzkin

Frontiers in Physiology

doi 10.3389/fphys.2025.1630155

3,668 views

Original Research

Published on 25 Aug 2025

Long COVID-19 alters muscle architecture and muscle-tendon force transmission: a one-year longitudinal study

in Skeletal Physiology

Leandro Gomes de Jesus Ferreira
Isabella da Silva Almeida
Rochelle Rocha Costa
Gabrielle Vieira Roriz
Jeam Marcel Geremia
João Luiz Quagliotti Durigan
Rita de Cássia Marqueti

Frontiers in Physiology

doi 10.3389/fphys.2025.1641046

4,146 views

Systematic Review

Published on 30 Jul 2025

3D printed scaffolds loaded with BMP-2 for bone defect regeneration: a systematic review and meta-analysis

in Skeletal Physiology

Lei Li
Lishi Yang
Yue Yang
Jiayi Zhu
Rongnan Shi
Qi Deng
Jianxiong Wang
Fuhua Sun

Frontiers in Physiology

doi 10.3389/fphys.2025.1641937

2,128 views
1 citation

Review

Published on 15 Jul 2025

Osteocytes function as biomechanical signaling hubs bridging mechanical stress sensing and systemic adaptation

in Skeletal Physiology

Ma Yuze
Jin Hu
Lv Jun
Xu Cheng
Xin Tianwen
Zhang Junqiang

Frontiers in Physiology

doi 10.3389/fphys.2025.1629273

3,312 views
1 citation

Original Research

Published on 09 Jul 2025

Metamizole does not affect fracture healing in a murine ischemia model

in Skeletal Physiology

Christian Schönbeck
Janine Stutz
Sebastian T. Schreiber
Lukas Keller
Chiara Siep
Wolfgang Metzger
Mario Giorgi
Irene Sartini
Tobias Fritz
Tim Pohlemann

Frontiers in Physiology

doi 10.3389/fphys.2025.1630268

1,720 views

Original Research

Published on 04 Jul 2025

Age-dependent association between lifestyle oxidative balance score and bone mineral density in children and adolescents: evidence from the NHANES 2015–2018

in Skeletal Physiology

Suman Li
Yuan Mao

Frontiers in Physiology

doi 10.3389/fphys.2025.1618996

2,496 views

Systematic Review

Published on 02 Jul 2025

Platelet rich plasma injections for knee osteoarthritis: an overview of systematic reviews

in Skeletal Physiology

Lin Yi
Fei Qiu
Haiyuan Song
Huiyuan Huang
Guanghui Zhang

Frontiers in Physiology

doi 10.3389/fphys.2025.1598514

4,741 views
3 citations

Systematic Review

Published on 27 Jun 2025

Effect of high-intensity training on improving knee flexion strength and quality of life in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

in Skeletal Physiology

Bo Zhai
Yu Wang
Zhongliang Zhang
Qiang Wang

Frontiers in Physiology

doi 10.3389/fphys.2025.1561697

3,961 views

Original Research

Published on 09 Jun 2025

The association between aggregate index of systemic inflammation and DXA-measured body composition parameters in adolescents

in Skeletal Physiology

Haihua Wang
Luping Tao
Zhongxin Zhu

Frontiers in Physiology

doi 10.3389/fphys.2025.1612735

2,457 views
1 citation

Review

Published on 27 May 2025

TNF receptor-associated factors: promising targets of natural products for the treatment of osteoporosis

in Skeletal Physiology

Xicheng Yang
LiLi Zhao
YinQuan Pang

Frontiers in Physiology

doi 10.3389/fphys.2025.1527814

3,582 views
1 citation

143 articles

articles

Reliability of DIERS pedogait system for evaluating spatiotemporal gait parameters in knee osteoarthritis and its association with Achilles tendon stiffness asymmetry

Meta-analysis of comparative effects of mobile app–based digital rehabilitation versus traditional rehabilitation after total knee arthroplasty

Influence of adrenoceptor blocker treatment on fracture healing in osteoporotic and non-osteoporotic bone

Comparison of quadriceps femoris properties, surface electromyography parameters and foot posture asymmetries between patients with unilateral and bilateral knee osteoarthritis

The role of cell death in the physiological and pathological processes of skeletal muscle

Multiple pathways of the actin-myosin cycle in energy transduction and the release of orthophosphate in muscle

Non-neuronal cholinergic stimulation favors bone mass accrual

Meeting report: the inaugural muscle biology and cachexia conference at the University of Houston, May 18-20, 2025, Houston, Texas, USA

Single-cell sequencing reveals cellular heterogeneity and molecular mechanisms in tendon and enthesis injury repair

Pathophysiological mechanisms and emerging therapeutic strategies for muscle wasting: an integrative review

Characterization of human skeletal stem cells in closed and open tibia fractures: a single center pilot study

Identification and functional analysis of circular RNAs in intervertebral disc lesion tissues from spinal tuberculosis patients

Correlation analysis of osteoporosis and vertebral endplate defects using CT and MRI imaging: a retrospective cross-sectional study

Cuproptosis related genes in immune infiltration and treatment of osteoporosis by bioinformatic analysis and machine learning methods

Deep behavioral phenotyping tracks functional recovery following tibia fracture in mice

Long COVID-19 alters muscle architecture and muscle-tendon force transmission: a one-year longitudinal study

3D printed scaffolds loaded with BMP-2 for bone defect regeneration: a systematic review and meta-analysis

Osteocytes function as biomechanical signaling hubs bridging mechanical stress sensing and systemic adaptation

Metamizole does not affect fracture healing in a murine ischemia model

Age-dependent association between lifestyle oxidative balance score and bone mineral density in children and adolescents: evidence from the NHANES 2015–2018

Platelet rich plasma injections for knee osteoarthritis: an overview of systematic reviews

Effect of high-intensity training on improving knee flexion strength and quality of life in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

The association between aggregate index of systemic inflammation and DXA-measured body composition parameters in adolescents

TNF receptor-associated factors: promising targets of natural products for the treatment of osteoporosis