A case of epithelioid hemangioendothelioma of right femoral artery misdiagnosed as arterial occlusion

Zhengqi Shao^1,2Jian Wang³Hongzhi Hu^1*Baichuan Wang^1*

• ¹Department of Orthopaedics, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
• ²Department of Oncology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hebei Province, China
• ³Department of Vascular Surgery, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hebei Province, China

Epithelioid hemangioendothelioma (EHE) is a rare and locally aggressive tumour of vascular endothelial origin, with an estimated prevalence of less than 1 in a million.EHE can arise in any part of the body, with the most common being the liver, lungs, and skeleton, whereas EHE occurring in the blood vessels of the extremities is rare. This article reports a rare case of primary epithelioid hemangioendothelioma (EHE) of the right femoral artery. The patient was initially misdiagnosed with lower limb arterial occlusion and treated with stenting and other therapies, then symptoms recurred and the diagnosis of EHE was confirmed by pathological biopsy.This tumour is very rare and accounts for approximately 1% of all vascular tumours. Our patient was considered to have WWTR1-CAMTA1 fusion EHE after the pathological findings showed CD31(+),CD34(-),CAMTA(+).The treatment of EHE is mainly surgical.In our case,the patient underwent resection of the lesion area and the surrounding soft-tissue mass,and was treated with a left saphenous vein graft.The patient was then treated with a stenting of the left saphenous vein.