SYSTEMATIC REVIEW article

Front. Surg.

Sec. Orthopedic Surgery

Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1594217

This article is part of the Research TopicNew Perspectives and Innovative Techniques in Contemporary Spine Surgery - Volume IIView all 4 articles

Incidence of New Osteoporotic Adjacent Vertebral Body Fractures. A Comparison between Conservative Treatment and Vertebral Body Augmentation (vertebroplasty, kyphoplasty): A Systematic Review and Meta-analysis

Provisionally accepted
Panagiotis KorovessisPanagiotis Korovessis1*Vasileios SyrimpeisVasileios Syrimpeis2Alkis KorovesisAlkis Korovesis3Georgios DimakopoulosGeorgios Dimakopoulos4
  • 1Spine and Orthopaedics Department, Olympion General Hospital, Patras, Greece
  • 2Embedded Systems Design and Applications (ESDA) Laboratory, Department of Informatics and Telecommunications, University of the Peloponnese, Greece., Patras, Greece
  • 3University of Patras, Patras, Western Greece, Greece
  • 4Biostats, Epirus Science and Technology Park Campus, University of Ioannina, Ioannina, Greece

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To compare the incidence of New Adjacent Vertebral Fractures (ANVFs) in elderly patients with Osteoporotic Vertebral Compression Fractures (OVCFs) undergoing either percutaneous vertebral augmentation-via Vertebroplasty (PVP) or Kyphoplasty (PKP)-or Conservative Treatment (CT). Additionally, this study aims to identify potential risk factors associated with ANVFs.The incidence of ANVFs does not significantly differ between patients managed with CT and those treated with PVP or PKP. This meta-analysis, for the selected RCTs, shows that vertebral augmentation is associated with a lower incidence of ANVFs compared to CT. On the other hand, in the retrospective studies group there was no significant difference in the incidence of ANVFs between the two treatment groups (CT vs PKP/PVP).Variations in study parameters, such as patient demographics and surgical techniques, may have affected these results. Further high-quality studies are needed to better understand the long-term effects of different treatment strategies on the incidence of ANVFs.

Keywords: Adjacent fracture, Kyphoplasty, Vertebroplasty, Adjacent, Vertebra fracture

Received: 15 Mar 2025; Accepted: 17 Apr 2025.

Copyright: © 2025 Korovessis, Syrimpeis, Korovesis and Dimakopoulos. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Panagiotis Korovessis, Spine and Orthopaedics Department, Olympion General Hospital, Patras, Greece

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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