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CASE REPORT article

Front. Surg.

Sec. Surgical Oncology

Case report Mammary myofibroblastic sarcoma with lung metastasis: a case report and literature review

Provisionally accepted
Miri RyuMiri Ryu1Youn Joo JungYoun Joo Jung1Seungju LeeSeungju Lee1Seok Kyeong KangSeok Kyeong Kang1Meehyun LeeMeehyun Lee1Jee Yeon KimJee Yeon Kim2Kyung Jin NamKyung Jin Nam3Kyeyoung LeeKyeyoung Lee4Ji Hyeon JooJi Hyeon Joo5Jae-Joon KimJae-Joon Kim6Hyun Yul KimHyun Yul Kim1,7*
  • 1Department of Surgery, Research institute for Convergence of biomedical science and technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea
  • 2Department of Pathology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea
  • 3Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea
  • 4Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine,, Yangsan, Republic of Korea
  • 5Department of Radiation Oncology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea
  • 6Department of Hematology and Oncology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea
  • 7Pusan National University Yangsan Hospital Nephrology Clinic, Yangsan-si, Republic of Korea

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Myofibroblastic sarcoma of the breast are rare, leading to very few reports on its prognosis or metastasis to other organs. We report a case of lung metastasis from mammary low-grade myofibroblastic sarcoma. A 55-year-old woman with no remarkable disease history visited a local clinic with a palpable mass in her left breast, persistent for 3 weeks. On vacuum-assisted excisional biopsy, the mass was diagnosed as a malignant phyllodes tumor. Thereafter, wide excision ensured a clear surgical margin, confirming myofibroblastic sarcoma. No additional treatments, such as chemotherapy or radiotherapy, were administered. Four years later, lung metastasis was detected on chest computed tomography. The patient underwent a wedge resection of the lung. Metastasis to the cervical lymph nodes was discovered 3 years later. Owing to tumor emboli, the patient died of brain infarction. No consensus guidelines for standard treatment exist owing to the disease scarcity. Surgical resection is the most reasonable treatment, however, additional therapies should be considered to prevent metastasis to other organs

Keywords: Breast, Lung, metastasis, Myofibroblastic, Sarcoma

Received: 04 Sep 2025; Accepted: 29 Dec 2025.

Copyright: © 2025 Ryu, Jung, Lee, Kang, Lee, Kim, Nam, Lee, Joo, Kim and Yul Kim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Hyun Yul Kim

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