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SYSTEMATIC REVIEW article

Front. Surg.

Sec. Genitourinary Surgery and Interventions

Enhanced recovery after surgery nursing improves postoperative outcomes in laparoscopic radical nephrectomy: a cumulative meta-analysis

Provisionally accepted
  • 1Ningxia Hui Autonomous Region Maternal and Child Health Hospital, Yinchuan, China
  • 2Hexi University, Zhangye, China

The final, formatted version of the article will be published soon.

Background: Renal carcinoma is a common malignant tumor of the urinary system worldwide. Given substantial evidence demonstrating the beneficial effects of Enhanced Recovery After Surgery (ERAS) care on recovery following laparoscopic radical nephrectomy for renal cancer, we conducted a systematic review and meta-analysis to summarize relevant studies and evaluate the application value of ERAS care in this context. Methods: We searched databases including PubMed, Embase, The Cochrane Library, Web of Science, OVID, CNKI, Wanfang Data, VIP, and the China Biological Literature Database (CBM) for clinical studies comparing ERAS care with traditional perioperative care in patients undergoing laparoscopic radical nephrectomy for renal cancer, up to December 2025. Two independent reviewers performed literature screening, data extraction, and quality assessment of the included studies. Cumulative meta-analysis was conducted using Stata version 12.0. Results: A total of 26 relevant studies were included, comprising 24 randomized controlled studies and 2 quasi-experimental studies, involving 2361 patients (1172 in the ERAS care group and 1189 in the traditional care group). The cumulative meta-analysis results indicated that patients receiving ERAS care experienced significantly earlier times to first anal exhaust, first feeding, first urination time after surgery, first defecation, catheter encumbrance time, first time out of bed activity, and removal time of drainage tube postoperatively. Furthermore, and postoperative hospital stay were shorter in the ERAS group. The ERAS group also demonstrated a lower overall incidence of postoperative total complications and higher patient satisfaction. Conclusion: The application of ERAS care in laparoscopic radical nephrectomy for renal cancer can accelerate postoperative recovery, shorten postoperative hospital stay, and reduce the incidence of postoperative complications. However, due to potential heterogeneity among the included studies, these conclusions warrant further validation by more high-quality research.

Keywords: Cumulative meta-analysis, Enhanced Recovery After Surgery Nursing, Eras, Nurse, radical nephrectomy

Received: 03 Oct 2025; Accepted: 29 Jan 2026.

Copyright: © 2026 Wang, Yan and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yu Gao

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