ORIGINAL RESEARCH article
Front. Surg.
Sec. Visceral Surgery
This article is part of the Research TopicEnhanced Recovery After Gastrointestinal SurgeryView all 8 articles
Application of Enhanced Recovery after Surgery in Laparoscopic Biliary Reoperation for Extrahepatic Bile Duct Stones
Provisionally accepted
- 1Second Affiliated Hospital of Soochow University, Suzhou, China
- 2Suzhou Industrial Park XingTang Hospital, Suzhou, China
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Objective: To evaluate the safety and efficacy of enhanced recovery after surgery (ERAS) protocols in laparoscopic biliary reoperations for extrahepatic bile duct stones. Methods: A total of 60 patients with prior biliary surgery were randomly assigned to either an ERAS group or a control group (n = 30 each). Both groups underwent laparoscopic bile duct exploration. Perioperative outcomes, inflammatory markers (CRP, IL-6), and nutritional indicators (prealbumin) were compared. Functional recovery, quality of life (SF-6), and complications were also assessed. Results: The ERAS group showed significantly shorter time to first flatus, faster ambulation and oral intake, lower pain scores, shorter hospital stays, and reduced hospitalization costs (P < 0.05). Patient satisfaction at discharge and 3 months postoperatively was significantly higher. SF-6 scores at 4 weeks showed better physical function, vitality, and general health in the ERAS group. CRP and IL-6 levels were lower, and prealbumin levels were higher postoperatively in the ERAS group (P < 0.05). The incidence of complications such as severe nausea and vomiting was lower in the ERAS group. Conclusions: ERAS is a safe and effective strategy in laparoscopic reoperation for extrahepatic bile duct stones. It significantly improves early recovery, reduces inflammation and costs, enhances patient satisfaction, and supports wider adoption of ERAS in hepatobiliary surgery.
Keywords: biliary reoperation, Eras, Extrahepatic bile duct stones, laparoscopic surgery, postoperative recovery
Received: 03 Nov 2025; Accepted: 19 Jan 2026.
Copyright: © 2026 Lin, Jiang, Zhuang, Wei, Li and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaoming Ma
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