CASE REPORT article
Front. Surg.
Sec. Reconstructive and Plastic Surgery
This article is part of the Research TopicState of the Art in Acute Care Surgery: Application, Innovation, and Future PerspectivesView all 20 articles
Negative pressure wound therapy for Perianal necrotizing fasciitis:case report and literature review
Provisionally accepted
- 1Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, China
- 2Nanjing University of Chinese Medicine, Nanjing, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Perianal necrotizing fasciitis (PNF) is a life-threatening soft tissue infection with high mortality. Despite the established role of radical debridement, outcomes are often hindered by late diagnosis and suboptimal postoperative care. While negative pressure wound therapy (NPWT) promotes complex wound healing, its synergistic application with radical debridement in PNF requires further validation. We report a case of extensive PNF that demonstrated the limitations of traditional interventions. By utilizing an integrated strategy of extended-incision radical debridement and early NPWT, we achieved rapid infection control and accelerated wound healing. This case suggests that such a combined technical framework can overcome clinical challenges and significantly improve PNF prognosis.
Keywords: Fecal diversion, Fournier's gangrene, Negative pressure wound therapy (NPWT), perianal necrotizing fasciitis, Radical debridement, Vacuum-assisted closure (VAC)
Received: 17 Nov 2025; Accepted: 04 Feb 2026.
Copyright: © 2026 Ma, Zhang, Xue, Liu, Chen, Wang and Ge. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Bei Zhang
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.