ORIGINAL RESEARCH article
Front. Vet. Sci.
Sec. Animal Nutrition and Metabolism
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1591214
Efficacy of a new biosynthetic bacterial 6-phytase on growth performance, bone mineralization and nutrient digestibility in nursery and growing pigs
Provisionally accepted
- 1Adisseo France S.A.S., European Laboratory of Innovation, Science and Expertise, 69190 Saint-Fons, France
- 2Adisseo France S.A.S, 92160 Antony, France
- 3Zootests, Parc Technologique du Zoopôle, 5 Rue Gabriel Calloet-Kerbat, 22440 Ploufragan, France
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Two studies were carried out to investigate the effects of a novel bacterial biosynthetic 6phytase on growth performance, bone mineralization and apparent total digestibility (ATTD) of phosphorus (P) in weaned piglets and growing pigs. They were carried out on 192 weaned piglets with initial body weight (BW): 9.3 ± 1.2 kg (33 days of age) and 360 growing pigs with initial BW: 33.3 ± 4.9 kg (85 days) for 43 and 84 days, respectively, according to a randomized complete block design with three treatments. The treatments were a positive control (PC) diet formulated to meet nutrient requirements, a negative control (NC) diet reduced similarly in calcium (Ca) and digestible P by 0.12% points in piglets and by 0.14, 0.11 and 0.10% points, respectively in phases 1, 2 and 3 in growing pigs, compared with PC diet; and NC diet supplemented with the new 6-phytase at 500 phytase units (FTU) per kg diet (PHY). The mineral depletion decreased final BW (-6.3%, p = 0.005, -3.0%, p < 0.05), Average daily gain (ADG: -8.8%, p = 0.003, -4.3%, p < 0.05), bone ash content (-24.7%, p < 0.001 , -9.6%, p = 0.005), bone P content (-24.6%, p < 0.001,-6.5%, p = 0.11) and ATTD of P (-11.8% points, p < 0.001, -9.2% points, p < 0.001) and increased feed-to-gain (F:G) ratio (+2.1%, p < 0.001, +4.7%, p < 0.05) in weaned piglets and growing pigs, respectively. Compared to animals fed the NC diet, phytase addition improved the final BW (+6.5%, p = 0.006, +2.3%, p < 0.05), ADG (+9.0%, p = 0.005, +3.4%, p < 0.05), F:G ratio (-3.1%, p < 0.001, -2.4%, p < 0.05), metacarpal ash content (+27.6%, p < 0.001, +9.3%, p = 0.004) and metacarpal P content (+29.3%, p < 0.001, +7.0%, p = 0.06) in weaned piglets and growing pigs, respectively. The final BW, ADG and bone ash content in animals fed NC diet supplemented with phytase were comparable to animals fed the PC diet.
Keywords: efficacy, phytase, mineralization, piglets, pigs
Received: 10 Mar 2025; Accepted: 23 Jul 2025.
Copyright: © 2025 Jlali, Hincelin, Manceaux and Ozbek. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Maamer Jlali, Adisseo France S.A.S., European Laboratory of Innovation, Science and Expertise, 69190 Saint-Fons, France
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