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CASE REPORT article

Front. Vet. Sci.

Sec. Veterinary Neurology and Neurosurgery

Volume 12 - 2025 | doi: 10.3389/fvets.2025.1597258

This article is part of the Research TopicCase Reports in Veterinary Neurology and Neurosurgery, Volume IIView all 9 articles

Case report: Generalized motor tonic seizures characterized by paroxysmal fast activity on EEG in a Tonkinese cat

Provisionally accepted
  • 1Wroclaw University of Environmental and Life Sciences, Wrocław, Poland
  • 2Neuroteam Veterinary Specialist Clinic, Wrocław, Poland, Wroclaw, Poland

The final, formatted version of the article will be published soon.

Epilepsy is one of the most common neurological disorders in cats, affecting 1%-2% of the feline population. Feline epilepsy can often be managed with standard anti-seizure medications, which typically offer moderate to good seizure control. However, a small subset of cats may experience drug-resistant epilepsy and require alternative treatment options. The scientific understanding of the mechanisms underlying feline epilepsy has not yet reached the applicability seen in human studies. A deeper understanding of feline epilepsy will aid in developing effective treatment strategies. Electroencephalography (EEG) is an important tool for extending veterinary epilepsy classification. In the presented case, the disease was classified as idiopathic epilepsy with a Tier III confidence level according to the International Veterinary Epilepsy Task Force classification. The seizures were further characterized as primarily generalized tonic, with occasional focal seizures also observed, and the condition met the criteria for drug-resistant epilepsy. EEG findings revealed typical spike, sharp and slow wave, and polyspike activity, along with atypical paroxysmal fast activity. Non-standard treatment with phenytoin demonstrated potential efficacy in this case.

Keywords: feline epilepsy, tonic epilepsy, Electroencephalography, paroxysmal fast activity, Phenytoin

Received: 20 Mar 2025; Accepted: 04 Aug 2025.

Copyright: © 2025 Brewińska, Drobot and Wrzosek. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Laura Brewińska, Wroclaw University of Environmental and Life Sciences, Wrocław, Poland

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