BRIEF RESEARCH REPORT article
Front. Vet. Sci.
Sec. Veterinary Infectious Diseases
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1598231
This article is part of the Research TopicThe application of new technologies such as new vaccines, therapeutic cytokines and antibodies, and antiviral drugs in the prevention and treatment of animal infectious diseasesView all 16 articles
Assessing the effect of orally administered Ivermectin on viremia and shedding of porcine reproductive and respiratory syndrome virus in growing pigs under field conditions
Provisionally accepted
- 1Walcott Veterinary Clinic, Iowa, United States
- 2Iowa State University, Ames, Iowa, United States
- 3Bimeda Biologicals, Minnesota, United States
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Despite over thirty years of research and numerous products, techniques, and physical barriers to prevent PRRSV outbreaks, significant economic losses due to PRRSV continue to plague the industry. The continued losses experienced in weaned pig populations due to PRRSV outbreaks suggest that new alternative therapies to control PRRSV need to be investigated. This field study evaluated the effect of orally administered Ivermectin on mitigating PRRSV in wean-to-market pigs. Compared to controls, Ivermectin-treated groups showed a numerical reduction in PRRSV detection in oral fluid samples at 8 of 9 sampling time points and had fewer PRRSV-positive pens during the first three weeks post-administration. Ivermectin-treated groups did not demonstrate a reduction in log10 viral concentration in serum.
Keywords: PRRSV, Ivermectin, Viremia, shedding, Swine, wean-to-market, Oral fluids
Received: 22 Mar 2025; Accepted: 18 Jun 2025.
Copyright: © 2025 Allison, Gauger, Osemeke and Lawrence. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Grant Allison, Walcott Veterinary Clinic, Iowa, United States
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