REVIEW article
Front. Vet. Sci.
Sec. Veterinary Clinical, Anatomical, and Comparative Pathology
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1618260
Advance on Establishment of Pathological Model of Ulcerative Colitis
Provisionally accepted
- Inner Mongolia Agricultural University, Hohhot, China
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Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), is a chronic, relapsing inflammatory disorder of the gastrointestinal tract with multifactorial etiology. The etiology and pathogenesis of ulcerative colitis are diverse, so it is crucial to explore the pathogenesis through animal models. Selecting appropriate animal models is critical for advancing our understanding of UC pathogenesis and therapeutic strategies. This review discusses various UC animal models and compares their characteristics in relation to disease mechanisms and therapeutic research.
Keywords: Crohn's disease, ulcerative colitis, Animal Models, etiology, Pathogenesis
Received: 29 Apr 2025; Accepted: 13 Aug 2025.
Copyright: © 2025 Yang, Gao and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lan Yang, Inner Mongolia Agricultural University, Hohhot, China
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