REVIEW article
Front. Vet. Sci.
Sec. Veterinary Pharmacology and Toxicology
This article is part of the Research TopicNatural Compounds in Veterinary TherapeuticsView all 12 articles
Research Progress on the Prevention and Treatment of Zearalenone Poisoning in Animals Using Natural Products
Provisionally accepted
- 1Jilin Agricultural Science and Technology University, Jilin, China
- 2Northeast Agricultural University, Harbin, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Zearalenone (ZEA) is a non-steroidal estrogenic mycotoxin produced by Fusarium fungi, widely present in cereal feeds such as corn, barley, wheat, and sorghum. It not only impacts agricultural production and feed safety but also poses a serious threat to animal health. Extensive research demonstrates that natural products can effectively mitigate the toxic effects of zearalenone. This paper reviews zearalenone's physicochemical properties and toxicological effects, with a focus on advances in the research on reducing zearalenone toxicity through plant, microbial, and mineral-derived natural products. The aim is to provide theoretical references for developing more efficient and safer zearalenone detoxification agents.
Keywords: Zearalenone, Toxicity, Natural Products, Detoxification methods, Bee pollen
Received: 21 Sep 2025; Accepted: 03 Nov 2025.
Copyright: © 2025 Liu, Zhang, Piao, Sun and SHI. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Guangliang SHI, shiguangliang@neau.edu.cn
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.