About this Research Topic
Endocrine disorders range from more common conditions such as diabetes or hypothyroidism to the rare diseases such as adrenocortical carcinoma or pheochromocytoma. Study of endocrine disorders has been challenging because efforts to create cell lines have had limited success and mouse models often demonstrate fundamental differences from human tissues. Over the past decade, 3-dimensional models have allowed researchers to overcome many of the barriers of long-term in vitro cultures of human tissues. In this collection, we will highlight the use of 3-dimensional models, such as organoids and organotypic cultures, to study endocrine development and disease. We welcome papers describing innovative basic and translational research using 3-dimensional models to characterize endocrine systems.
Keywords: cancer endocrinology, organoid models, cancer, 3D models, endocrine
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.