Transient Receptor Potential Channels (TRP): Signal Transduction

We are honoured to present ‘Transient Receptor Potential Channels (TRP): Signal Transduction’ as part of the Frontiers in Molecular Biosciences Ion Channels Research Topic Series.

Ion Channels are integral pore-forming membrane proteins that play an essential role in the biological processes involved in regulation, activation and maintenance of the nervous system. These channels form one half of the family of Ionophore membrane proteins, and facilitate the essential passage of ions across the cellular membrane.

Excitable cells such as neurons and muscle cells rely on the action of ion channels to recognise a variety of extracellular signals, and subsequently transform these stimuli into electrical signals essential for cellular function.

In light of the inherent role Ion Channels play within the cell and human body as a whole, their function and dysfunction is often naturally involved in the pathways intrinsic in many diseases, and thus are an important drug and therapeutic target.

This Research Topic aims to bring together a community of like-minded field-experts, to help stimulate discussion and the sharing of ideas to fuel the scientific direction of future Ion Channel research within the field of cellular biochemistry. We invite submissions that contribute to the improvement of our collective understanding of the role TRP Channels play in human health and disease, and welcome contributions covering all aspects of signalling transduction research in relation to TRP Channels.