Molecular Mechanisms of the Host Immune Response to Toxoplasma gondii Infection

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ORIGINAL RESEARCH

Published on 24 Jun 2025

Dual single-cell and bulk RNA sequencing reveal transcriptional profiles underlying heterogenous host-parasite interactions in human peripheral blood mononuclear cells

Praveena Chandrasegaran
Bekir Faydaci
Barbara Shih
Musa A. Hassan

doi 10.3389/fimmu.2025.1582645

622 views

ORIGINAL RESEARCH

Accepted on 02 Jun 2025

Toxoplasma gondii virulence in mice is determined by the pseudokinase ROP5B and countered by an IRG-GBP protein interplay

Shishir Singh
Mateo Murillo-León
Aura Maria Bastidas Quintero
Florence Melbert
Klaus Pfeffer
Daniel Degrandi
Tobias Steinfeldt

doi 10.3389/fimmu.2025.1593785

287 views

ORIGINAL RESEARCH

Published on 29 Aug 2024

Inflammatory response and parasite regulation in acute toxoplasmosis: the role of P2X7 receptor in controlling virulent atypical genotype strain of Toxoplasma gondii

Thuany Prado-Rangel
Aline Cristina Abreu Moreira-Souza
Sthefani Rodrigues Batista da Silva
Thais Barboza-Araujo
Archimedes Barbosa Castro-Junior
Isalira Peroba Rezende Ramos
Christina Maeda Takiya
Rossiane Claudia Vommaro
Robson Coutinho-Silva

doi 10.3389/fimmu.2024.1452828

1,301 views
2 citations

REVIEW

Published on 10 May 2024

New advances in immune mechanism and treatment during ocular toxoplasmosis

Zijian Chen
Shizhou Cheng
Xiaoming Chen
Zuhai Zhang
Yanhua Du

doi 10.3389/fimmu.2024.1403025

4,244 views
2 citations

REVIEW

Published on 07 Feb 2024

IFNs in host defence and parasite immune evasion during Toxoplasma gondii infections

Carsten G. K. Lüder

doi 10.3389/fimmu.2024.1356216

2,919 views
3 citations

ORIGINAL RESEARCH

Published on 27 Jul 2023

scDual-Seq of Toxoplasma gondii-infected mouse BMDCs reveals heterogeneity and differential infection dynamics

Franziska Hildebrandt
Mubasher Mohammed
Alexis Dziedziech
Amol K. Bhandage
Anna-Maria Divne
Fredrik Barrenäs
Antonio Barragan
Johan Henriksson
Johan Ankarklev

doi 10.3389/fimmu.2023.1224591

2,480 views
3 citations

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Frontiers in Immunology

Frontiers in Immunology

Parasite Immunology

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