Research Topic

Biomimetic fabrication for 3D biology

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About this Research Topic

Biofabrication is a new field combining principles of engineering, biology, and material science that holds the promise to change the gear box of many biotechnological disciplines. Initial reports related to biofabrication principles date back to the beginning of the new millennium. Since then, the field of ...

Biofabrication is a new field combining principles of engineering, biology, and material science that holds the promise to change the gear box of many biotechnological disciplines. Initial reports related to biofabrication principles date back to the beginning of the new millennium. Since then, the field of biofabrication has grown exponentially. This not only includes bioprinting, but also a number of other approaches where cells and biomaterials have been used in combination or alone to fabricate new constructs for tissue engineering and regenerative medicine applications. This field also grown to include new in vitro models for pharmaceutical screening, and more in general new building blocks that serve as inspiration for a number of other life science sectors, including food, cosmetic, detection and diagnostic industries.

Biofabrication may today also comprise efforts in more futuristic developments where devices are
made by cellularised constructs to furnish to them features that are normally hard to replicate with electronic, mechanical and chemical components such as senses. Bioinspired actuators are a clear example of such strategy. The application of biofabrication represents one of the most rapidly advancing areas of biomedical sciences in which bioengineers, clinicians, and scientists are contributing in large to
human health care. An increasing number of professionals from the most disparate disciplines are gaining interest in this new field. This has resulted in an increase of developed strategies for the regeneration of tissues as well as the generation of in vitro 3D models that hold the potential to recapitulate more closely the complexity and heterogeneity of tissues and organs in the human body.

Potential topics include, but are not limited to:
• Development and characterization of novel biomaterials for Biofabrication
application
• Design, realization and characterization of novel biofabricated structure
• Novel biofabrication approach or platform


Keywords: biofabrication, biomaterials, software modelling, bioreactor, in silico cell models


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