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This Research Topic aims to collect all the Case Reports submitted to the Neurological Biomarkers section. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.

Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered:

1) RARE case with TYPICAL features.

2) FREQUENT case with ATYPICAL features.

3) Cases with a convincing response to new treatments, i.e. single case of off-label use.

Case Report format:

- Maximum word count: 3000 words.

- Title: Case Report: “area of focus”

- Abstract.

- Introduction: including what is unique about the case and medical literature references.

- Case description: including de-identified patient information, relevant physical examination and other clinical findings, relevant past interventions, and their outcomes.

- A figure or table showcasing a timeline with relevant data from the episode of care.

- Diagnostic assessment, details on the therapeutic intervention, follow-up, and outcomes, as specified in the CARE guidelines.

- Discussion: strengths and limitations of the approach to the case, discussion of the relevant medical literature (similar and contrasting cases), take-away lessons from the case.

- Patient perspective.

Please, note that authors are required to obtain written informed consent from the patients (or their legal representatives) for the publication.


Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered.



Maximum word count: 3,000

Maximum number of display items (figures, tables, or videos): 4.

Minimum number of patients: 2.



Authors should follow the CARE guidelines (https://www.care-statement.org/) and submit a completed CARE checklist as a supplementary file (template available here: http://data.care-statement.org/wp-content/uploads/2019/03/CARE-checklist-English-2013.pdf)



Case Report format:

- Title: Case Report: “area of focus”

- Abstract.

- Introduction: including what is unique about the case and medical literature references.

- Case description: including de-identified patient information, relevant physical examination and other clinical findings, relevant past interventions and their outcomes.

- A figure or table showcasing a timeline with relevant data from the episode of care.

- Diagnostic assessment, details on the therapeutic intervention, follow-up, and outcomes, as specified in the CARE guidelines.

- Discussion: strengths and limitations of the approach to the case, discussion of the relevant medical literature (similar and contrasting cases), take-away lessons from the case.

- Patient perspective.



Please, note that authors are required to obtain written informed consent from the patients (or their legal representatives) for the publication.



IMPORTANT: Any Case Report submitted to the Neurological Biomarkers section outside this collection might experience delays, as they will be sent for assessment to the Specialty Chief Editor prior to beginning the peer review

Keywords: Neurological Biomarkers, Case Reports


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

This Research Topic aims to collect all the Case Reports submitted to the Neurological Biomarkers section. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.

Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered:

1) RARE case with TYPICAL features.

2) FREQUENT case with ATYPICAL features.

3) Cases with a convincing response to new treatments, i.e. single case of off-label use.

Case Report format:

- Maximum word count: 3000 words.

- Title: Case Report: “area of focus”

- Abstract.

- Introduction: including what is unique about the case and medical literature references.

- Case description: including de-identified patient information, relevant physical examination and other clinical findings, relevant past interventions, and their outcomes.

- A figure or table showcasing a timeline with relevant data from the episode of care.

- Diagnostic assessment, details on the therapeutic intervention, follow-up, and outcomes, as specified in the CARE guidelines.

- Discussion: strengths and limitations of the approach to the case, discussion of the relevant medical literature (similar and contrasting cases), take-away lessons from the case.

- Patient perspective.

Please, note that authors are required to obtain written informed consent from the patients (or their legal representatives) for the publication.


Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered.



Maximum word count: 3,000

Maximum number of display items (figures, tables, or videos): 4.

Minimum number of patients: 2.



Authors should follow the CARE guidelines (https://www.care-statement.org/) and submit a completed CARE checklist as a supplementary file (template available here: http://data.care-statement.org/wp-content/uploads/2019/03/CARE-checklist-English-2013.pdf)



Case Report format:

- Title: Case Report: “area of focus”

- Abstract.

- Introduction: including what is unique about the case and medical literature references.

- Case description: including de-identified patient information, relevant physical examination and other clinical findings, relevant past interventions and their outcomes.

- A figure or table showcasing a timeline with relevant data from the episode of care.

- Diagnostic assessment, details on the therapeutic intervention, follow-up, and outcomes, as specified in the CARE guidelines.

- Discussion: strengths and limitations of the approach to the case, discussion of the relevant medical literature (similar and contrasting cases), take-away lessons from the case.

- Patient perspective.



Please, note that authors are required to obtain written informed consent from the patients (or their legal representatives) for the publication.



IMPORTANT: Any Case Report submitted to the Neurological Biomarkers section outside this collection might experience delays, as they will be sent for assessment to the Specialty Chief Editor prior to beginning the peer review

Keywords: Neurological Biomarkers, Case Reports


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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