Obesity and Cardiovascular Disease

Obesity is a complicated, multifactorial disease of epidemic proportions. It is well established that obesity will promote conditions such as dyslipidemia, type II diabetes, and hypertension with a resulting increased risk of major cardiovascular events. However, obesity has its own pathophysiology and is a recurrent, chronic non-communicable disease.

Led by an international team of subject experts, this research topic will explore obesity and cardiovascular disease with a focus on the underlying pathophysiology. Sub-themes include but are not limited to:
• Adipocyte distribution and resulting metabolic or inflammatory consequences
• Adipocyte and vasculature cross-talk
• Extracellular vesicles in the plaque process
• Mitochondria dysfunction

Keywords: obesity, cardiovascular, adipose tissue, inflammation, metabolic consequences, disease burden

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.