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Manuscript Submission Deadline 24 April 2024

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Periodontal diseases are a chronic, inflammatory condition that impacts the supporting structures of the teeth, which could eventually lead to tooth loss. It is estimated that periodontal diseases affect up to 50% of the adult population, making it a widespread problem. Recent research has highlighted the importance of sex and aging as potential risk factors, which opens new avenues for identifying personalized treatments.

Despite widespread recognition that periodontal diseases affect both males and females differently and that age plays a significant role in the development of the disease, there is still a lack of clarity on how to best manage these differences for optimal outcomes. Given that the global population is aging and periodontitis incidence increases with age, there is an urgent need for tailored treatment options. This Research Topic aims to address this issue by bringing together experts to explore sex and aging-related differences in periodontal diseases and their implications for precision dentistry.

This Research Topic welcomes submissions that investigate the sex and age-related differences in periodontal diseases from various perspectives, including the clinical, basic science, epidemiology, and translational aspects. Specific themes to be addressed may include, but are not limited to, the following:

• Age-related changes in the oral microbiome and its impact on periodontal health
• Sex and age-related differences in the host immune response to periodontal diseases
• The influence of sex and aging on periodontal disease risk factors and comorbidities
• New technological advances in the diagnosis and treatment of periodontal diseases based on sex and age-related differences
• The role of genetics/genomics in the intersection of sex and aging on periodontal disease

This Research Topic welcomes original research, reviews, and clinical studies that contribute to our understanding of the sex and aging-related differences in periodontal diseases. Authors are encouraged to submit manuscripts that provide novel insights into the pathobiology of periodontal diseases, as well as interventions and treatments that take into account the sex and age determinants. Case reports that highlight the unique presentation of periodontal diseases between males and females and across different age groups are also welcome.

Keywords: Periodontal diseases, Chronic Inflammation, Sex Differences, Aging, Tooth Loss, Age-related Changes


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Periodontal diseases are a chronic, inflammatory condition that impacts the supporting structures of the teeth, which could eventually lead to tooth loss. It is estimated that periodontal diseases affect up to 50% of the adult population, making it a widespread problem. Recent research has highlighted the importance of sex and aging as potential risk factors, which opens new avenues for identifying personalized treatments.

Despite widespread recognition that periodontal diseases affect both males and females differently and that age plays a significant role in the development of the disease, there is still a lack of clarity on how to best manage these differences for optimal outcomes. Given that the global population is aging and periodontitis incidence increases with age, there is an urgent need for tailored treatment options. This Research Topic aims to address this issue by bringing together experts to explore sex and aging-related differences in periodontal diseases and their implications for precision dentistry.

This Research Topic welcomes submissions that investigate the sex and age-related differences in periodontal diseases from various perspectives, including the clinical, basic science, epidemiology, and translational aspects. Specific themes to be addressed may include, but are not limited to, the following:

• Age-related changes in the oral microbiome and its impact on periodontal health
• Sex and age-related differences in the host immune response to periodontal diseases
• The influence of sex and aging on periodontal disease risk factors and comorbidities
• New technological advances in the diagnosis and treatment of periodontal diseases based on sex and age-related differences
• The role of genetics/genomics in the intersection of sex and aging on periodontal disease

This Research Topic welcomes original research, reviews, and clinical studies that contribute to our understanding of the sex and aging-related differences in periodontal diseases. Authors are encouraged to submit manuscripts that provide novel insights into the pathobiology of periodontal diseases, as well as interventions and treatments that take into account the sex and age determinants. Case reports that highlight the unique presentation of periodontal diseases between males and females and across different age groups are also welcome.

Keywords: Periodontal diseases, Chronic Inflammation, Sex Differences, Aging, Tooth Loss, Age-related Changes


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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