Omics in Endocrinology: from Biomarker Discovery to Targeting Therapeutic Strategies

Type 2 diabetes mellitus (T2DM) and thyroid disease (TD) are two common endocrinological and related metabolic diseases. Obesity is associated with the incidence of these metabolic diseases. Thyroid hormones play a critical role in regulating glucose homeostasis, insulin sensitivity, and pancreatic beta-cell function. Recently, advances in multi-omics approaches including metabolomics have provided insight into the science of biomarker discovery and understanding of the metabolic biochemical pathways dysregulated in several diseases.

We invite researchers to contribute original research and review articles investigating recent advances in aspects regarding multi–omic research on endocrinological and metabolic diseases including thyroid disease, diabetes, and obesity.
The association of T2DM, obesity, and thyroid diseases is unlikely a simple coincidence and requires a better understanding of the dysregulated metabolites, and biochemical pathways, and thus biomarker discovery and targeting therapy.

Submissions will be focusing on, but are not limited to, the following:
• Multi-omics approach to investigate the metabolic alterations associated with endocrinological and metabolic diseases.
• Exploring the metabolomic profile of patients with more than metabolic diseases.
• Investigating the changes in the biochemical pathway involved in the pathophysiology of endocrinological and metabolic diseases.
• The application of bioinformatics and artificial intelligence to mine new innovative strategies and biomarkers for endocrinological and metabolic diseases