Vaccines and Therapeutics Utilizing New Adjuvants and Potential Inhibitors to Target Emerging Infectious Diseases

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BRIEF RESEARCH REPORT

Published on 04 Apr 2025

A selective C5a-derived peptidomimetic enhances IgG response following inactivated SARS-CoV-2 immunization and confers rapid disease resolution following murine coronavirus infection

Andrew J. Neville
Mackenzie E. Conrin
Thomas T. Schulze
Paul H. Davis

doi 10.3389/fimmu.2025.1470034

1,021 views

ORIGINAL RESEARCH

Published on 13 Feb 2025

Designing a potent multivalent epitope vaccine candidate against Orientia tsutsugamushi via reverse vaccinology technique - bioinformatics and immunoinformatic approach

Subhasmita Panda
Subrat Kumar Swain
Basanta Pravas Sahu
Soumya Ranjan Mahapatra
Jyotirmayee Dey
Rachita Sarangi
Anu Vinod Ranade
Namrata Mishra

doi 10.3389/fimmu.2025.1513245

845 views

ORIGINAL RESEARCH

Published on 07 Feb 2025

Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters

Yongjun Sui
Swagata Kar
Bhavna Chawla
Tanya Hoang
YuanKai Yu
Shannon M. Wallace
Hanne Andersen
Jay A. Berzofsky

doi 10.3389/fimmu.2025.1514845

1,117 views

ORIGINAL RESEARCH

Published on 28 Jan 2025

Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches

Guneswar Sethi
Young Kyu Kim
Su-Cheol Han
Jeong Ho Hwang

doi 10.3389/fimmu.2024.1503853

1,528 views
1 citation

ORIGINAL RESEARCH

Published on 07 Jan 2025

Characteristics of humoral responses to the first coronavirus disease booster vaccine and breakthrough infection in central China: a multicentre, prospective, longitudinal cohort study

Junhong Xu
Youhua Yuan
Guohua Chen
Bing Ma
Yin Long Zou
Baoya Wang
Wenjuan Yan
Qi Zhang
Qiong Ma
3 more
Xiaohuan Zhang

doi 10.3389/fimmu.2024.1446751

809 views

ORIGINAL RESEARCH

Published on 06 Jan 2025

A gram-positive enhancer matrix particles vaccine displaying swine influenza virus hemagglutinin protects mice against lethal H1N1 viral challenge

Yufei Zhang
Pei Zhang
Xiaoyue Du
Xiaona Shi
Jinling Wang
Shuying Liu

doi 10.3389/fimmu.2024.1432989

863 views

ORIGINAL RESEARCH

Published on 11 Dec 2024

Phage-resistance alters Lipid A reactogenicity: a new strategy for LPS-based conjugate vaccines against Salmonella Rissen

Paola Cuomo
Chiara Medaglia
Angela Casillo
Antonio Gentile
Carmine Fruggiero
Maria Michela Corsaro
Rosanna Capparelli

doi 10.3389/fimmu.2024.1450600

856 views

ORIGINAL RESEARCH

Published on 26 Nov 2024

Intranasal trivalent candidate vaccine induces strong mucosal and systemic immune responses against Neisseria gonorrhoeae

Qin Lu
Hui Yang
Yanfeng Peng
Zeling Dong
Pujing Nie
Guangli Wang
Shilu Luo
Xun Min
Jian Huang
Meirong Huang

doi 10.3389/fimmu.2024.1473193

1,253 views

REVIEW

Published on 01 Oct 2024

Future applications of host direct therapies for infectious disease treatment

Ruth E. Thom
R V. D’Elia

doi 10.3389/fimmu.2024.1436557

1,760 views
8 citations

ORIGINAL RESEARCH

Published on 29 Aug 2024

The adjuvant BcfA activates antigen presenting cells through TLR4 and supports TFH and TH1 while attenuating TH2 gene programming

Mohamed M. Shamseldin
Kaitlin A. Read
Jesse M. Hall
Jasmine A. Tuazon
Jessica M. Brown
Myra Guo
Yash A. Gupta
Rajendar Deora
Kenneth J. Oestreich
Purnima Dubey

doi 10.3389/fimmu.2024.1439418

1,975 views

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Frontiers in Immunology

Vaccines and Molecular Therapeutics

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Articles

A selective C5a-derived peptidomimetic enhances IgG response following inactivated SARS-CoV-2 immunization and confers rapid disease resolution following murine coronavirus infection

Designing a potent multivalent epitope vaccine candidate against Orientia tsutsugamushi via reverse vaccinology technique - bioinformatics and immunoinformatic approach

Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters

Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches

Characteristics of humoral responses to the first coronavirus disease booster vaccine and breakthrough infection in central China: a multicentre, prospective, longitudinal cohort study

A gram-positive enhancer matrix particles vaccine displaying swine influenza virus hemagglutinin protects mice against lethal H1N1 viral challenge

Phage-resistance alters Lipid A reactogenicity: a new strategy for LPS-based conjugate vaccines against Salmonella Rissen

Intranasal trivalent candidate vaccine induces strong mucosal and systemic immune responses against Neisseria gonorrhoeae

Future applications of host direct therapies for infectious disease treatment

The adjuvant BcfA activates antigen presenting cells through TLR4 and supports TFH and TH1 while attenuating TH2 gene programming

Frontiers in Immunology

Vaccines and Molecular Therapeutics