Biofilm Dynamics: Interdisciplinary Insights into Microbial Interactions within the Context of Microbiomes and Host Health

Biofilms represent one of the most formidable challenges in microbiology and clinical medicine due to their inherent resilience and complex interactions within microbiomes. Despite significant advancements in our understanding of microbial communities, the intricate dynamics of biofilm formation and function remain elusive. Current research has highlighted the role of biofilms in both pathogenic and non-pathogenic contexts, yet many questions persist regarding their formation, maintenance, and impact on host health. Recent studies have begun to uncover the multifaceted interactions between biofilms and their microbial surroundings, but a comprehensive understanding of these dynamic structures is still lacking. Addressing these gaps is crucial for developing effective strategies to manage biofilm-associated infections and harnessing their potential benefits within the microbiome.

This research topic aims to delve into the intricate dynamics of biofilms, providing a nuanced understanding of microbial interactions within the expansive realm of microbiomes and their implications for host health. We seek to unravel the complexities of biofilm formation and function, offering insights into the role of non-pathogenic bacteria as integral components of the microbiome. By examining the interplay between biofilms and their microbial surroundings, this topic aims to contribute to a comprehensive comprehension of these dynamic structures. Furthermore, we aim to explore the multifaceted relationship between biofilms and host health, shedding light on potential links to both beneficial and detrimental outcomes.

To gather further insights into the dynamics of biofilms within microbiomes and their implications for host health, we welcome articles addressing, but not limited to, the following themes:
- Mechanisms of biofilm formation and maintenance
- Interactions between pathogenic and non-pathogenic bacteria within biofilms
- The role of biofilms in chronic infections and disease progression
- Biofilm-associated resistance to antimicrobial treatments
- The impact of biofilms on host immune responses
- Innovative methods for studying biofilm dynamics
- Potential therapeutic strategies targeting biofilms
- Bioinformatics approaches to understanding biofilm-associated microbiomes
- The influence of environmental factors on biofilm behavior and composition

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Systematic Review
• Technology and Code

Keywords: Extracellular matrix, Quorum sensing, Antimicrobial resistance, Biofilm architecture, Microbial community

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.