Spotlight on Myasthenia Gravis: Pathomechanisms, diagnostic challenges and novel therapeutic targets

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Articles

BRIEF RESEARCH REPORT

Published on 28 May 2025

Efficiency of cell-based assays in detecting AChR antibodies in myasthenia gravis sera with low antibody concentrations as determined by radioimmunoprecipitation assay

John S. Tzartos
Aigli G. Vakrakou
Katerina Karagiorgou
Vasiliki Zouvelou
Elisabeth Chroni
Valentina Damato
Francesca Beretta
Stavroula Salakou
Eirini Sfyroera
4 more
Socrates Tzartos

doi 10.3389/fimmu.2025.1459423

238 views

ORIGINAL RESEARCH

Published on 15 May 2025

Efficacy of MLN9708 (ixazomib) in experimental autoimmune myasthenia gravis and in anti-AChR producing primary thymic cell cultures from myasthenia gravis patients

Marina Mané-Damas
Abhishek Saxena
Gisela Nogales-Gadea
Jo Stevens
Shannen Vincken
Maarten van Beek
Nynke J. van den Hoogen
Elbert A. J. Joosten
Nick Willcox
5 more
Pilar Martinez-Martinez

doi 10.3389/fimmu.2025.1521432

734 views

BRIEF RESEARCH REPORT

Published on 14 Apr 2025

Complement inhibitor therapy in thymoma-associated myasthenia gravis: a real-world experience

Sofia Marini
Carmen Erra
Laura Fionda
Silvia Falso
Elena Rossini
Federico Habetswallner
Elisa Meacci
Martina Marini
Francesco Habetswallner
Raffaele Iorio

doi 10.3389/fimmu.2025.1562419

1,091 views

ORIGINAL RESEARCH

Published on 08 Apr 2025

The burden of disease in seronegative myasthenia gravis: a patient-centered perspective

Sophie Lehnerer
Regina Stegherr
Ulrike Grittner
Maike Stein
Lea Gerischer
Frauke Stascheit
Meret Herdick
Paolo Doksani
Andreas Meisel
Sarah Hoffmann

doi 10.3389/fimmu.2025.1555075

1,350 views

ORIGINAL RESEARCH

Published on 31 Mar 2025

Development of a refined experimental mouse model of myasthenia gravis with anti-acetylcholine receptor antibodies

Axel You
Léa S. Lippens
Odessa-Maud Fayet
Solène Maillard
Laureline Betemps
Antony Grondin
Jean-Thomas Vilquin
Nadine Dragin
Rozen Le Panse

doi 10.3389/fimmu.2025.1521382

1,659 views

ORIGINAL RESEARCH

Published on 23 Dec 2024

Cutoffs on severity metrics for minimal manifestations or better status in patients with generalized myasthenia gravis

Genya Watanabe
Yoshiki Takai
Yuriko Nagane
Tomoya Kubota
Manato Yasuda
Hiroyuki Akamine
Yosuke Onishi
Akiyuki Uzawa
Naoki Kawaguchi
12 more
Kimiaki Utsugisawa

doi 10.3389/fimmu.2024.1502721

1,601 views
2 citations

REVIEW

Published on 05 Dec 2024

A clinical perspective on muscle specific kinase antibody positive myasthenia gravis

Omar Keritam
Angela Vincent
Fritz Zimprich
Hakan Cetin

doi 10.3389/fimmu.2024.1502480

1,752 views

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Frontiers in Immunology

Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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Articles

Efficiency of cell-based assays in detecting AChR antibodies in myasthenia gravis sera with low antibody concentrations as determined by radioimmunoprecipitation assay

Efficacy of MLN9708 (ixazomib) in experimental autoimmune myasthenia gravis and in anti-AChR producing primary thymic cell cultures from myasthenia gravis patients

Complement inhibitor therapy in thymoma-associated myasthenia gravis: a real-world experience

The burden of disease in seronegative myasthenia gravis: a patient-centered perspective

Development of a refined experimental mouse model of myasthenia gravis with anti-acetylcholine receptor antibodies

Cutoffs on severity metrics for minimal manifestations or better status in patients with generalized myasthenia gravis

A clinical perspective on muscle specific kinase antibody positive myasthenia gravis

Frontiers in Immunology

Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders