The Current State of Knowledge on Asthma-COPD Overlap (ACO) in Clinical and Experimental Research: What Do We Know So Far?

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ORIGINAL RESEARCH

Published on 22 May 2025

Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a bronchoscopy endobronchial biopsy study

Surajit Dey
Wenying Lu
Prabuddha S. Pathinayake
Maddison Waters
Greg Haug
Josie Larby
Heinrich C. Weber
Peter A. B. Wark
Mathew Suji Eapen
Sukhwinder Singh Sohal

doi 10.3389/fimmu.2025.1531279

160 views

ORIGINAL RESEARCH

Published on 08 Oct 2024

Inflammatory profile of eosinophils in asthma-COPD overlap and eosinophilic COPD: a multi-omics study

Keeya Sunata
Jun Miyata
Yusuke Kawashima
Ryo Konno
Masaki Ishikawa
Yoshinori Hasegawa
Ryuta Onozato
Yo Otsu
Emiko Matsuyama
7 more
Koichi Fukunaga

doi 10.3389/fimmu.2024.1445769

3,433 views
1 citation

ORIGINAL RESEARCH

Published on 30 Jul 2024

Altered levels of IFN-γ, IL-4, and IL-5 depend on the TLR4 rs4986790 genotype in COPD smokers but not those exposed to biomass-burning smoke

Karla Jazmín Gutiérrez-Romero
Ramcés Falfán-Valencia
Alejandra Ramírez-Venegas
Rafael De Jesus Hernández-Zenteno
Fernando Flores-Trujillo
Raúl Sansores-Martínez
Espiridión Ramos-Martínez
Gloria Pérez-Rubio

doi 10.3389/fimmu.2024.1411408

1,687 views
2 citations

ORIGINAL RESEARCH

Published on 18 Jul 2024

Presence of sputum IgG against eosinophilic inflammatory proteins in asthma

Rundong Qin
Fei Long
Pingan Zhang
Renbin Huang
Hao Hu
Yubiao Guo
Zhenyu Zheng
Jing Xiao
Li He
1 more
Jing Li

doi 10.3389/fimmu.2024.1423764

1,417 views

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