Reactive oxygen species, as well as other reactive species such as nitric oxide, hydrogen sulfide, and oxidized lipids, have gained attention in the fields of biology and medicine due to their signaling roles. Significant progress has been made in comprehending their roles in embryonic development, metabolic pathways, lifespan regulation, and tissue regeneration. These species have nuanced roles in regulating all aspects of cell function. Dysregulation of redox homeostasis is a common pathophysiological condition in many diseases, metabolic dysfunction, and age-related degeneration. However, the specific targets of reactive species and how redox signals are transmitted in the cell are not well understood.
Redox signaling research addresses the fundamental redox processes that affect life and health. One aim is to uncover novel roles of reactive species such as oxygen, nitrogen or sulfur in developmental processes, metabolic pathways, and age-related degenerations. It explores how cells or organisms react to various reactive species under diverse conditions, and how they communicate with one another. A major objective is to understand the mechanisms of redox regulation of cellular processes. The interpretation of redox signaling involves identifying specific participants during redox transmission. These efforts are creating new opportunities to tackle global health and well-being challenges.
This topic aims to identify redox-sensitive targets to uncover the physiological significance of redox signaling in developmental processes, metabolic dysfunctions, and aging. To investigate redox control in metabolism, development, and aging from a single cell to model organisms including but not limited to bacteria, yeast, C. elegans, drosophila, arabidopsis, mice, and humans. Particularly interested in integrating the redox signaling transduction, such as the redox control of the specific targets that can be regulated by reversible oxidation, a novel regulatory posttranslational modification.
Keywords:
redox signaling, redox regulation, redox metabolism, reactive species, redox modification
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Reactive oxygen species, as well as other reactive species such as nitric oxide, hydrogen sulfide, and oxidized lipids, have gained attention in the fields of biology and medicine due to their signaling roles. Significant progress has been made in comprehending their roles in embryonic development, metabolic pathways, lifespan regulation, and tissue regeneration. These species have nuanced roles in regulating all aspects of cell function. Dysregulation of redox homeostasis is a common pathophysiological condition in many diseases, metabolic dysfunction, and age-related degeneration. However, the specific targets of reactive species and how redox signals are transmitted in the cell are not well understood.
Redox signaling research addresses the fundamental redox processes that affect life and health. One aim is to uncover novel roles of reactive species such as oxygen, nitrogen or sulfur in developmental processes, metabolic pathways, and age-related degenerations. It explores how cells or organisms react to various reactive species under diverse conditions, and how they communicate with one another. A major objective is to understand the mechanisms of redox regulation of cellular processes. The interpretation of redox signaling involves identifying specific participants during redox transmission. These efforts are creating new opportunities to tackle global health and well-being challenges.
This topic aims to identify redox-sensitive targets to uncover the physiological significance of redox signaling in developmental processes, metabolic dysfunctions, and aging. To investigate redox control in metabolism, development, and aging from a single cell to model organisms including but not limited to bacteria, yeast, C. elegans, drosophila, arabidopsis, mice, and humans. Particularly interested in integrating the redox signaling transduction, such as the redox control of the specific targets that can be regulated by reversible oxidation, a novel regulatory posttranslational modification.
Keywords:
redox signaling, redox regulation, redox metabolism, reactive species, redox modification
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.