Allergic diseases are a diverse group of conditions characterized by hypersensitivity reactions to otherwise harmless antigens, such as drugs, environmental, or food allergens. These conditions affect over 25% of the population in industrialized nations, posing significant challenges to public health and healthcare systems. Despite considerable advancements in recent decades, there remain critical gaps in our understanding, particularly concerning the diagnosis, treatment, and management of allergic patients. A deeper comprehension of the specific mechanisms underlying each allergic reaction is crucial for identifying distinct endotypes, which can aid in the discovery of specific biomarkers and potential therapeutic targets. The advent of omic sciences in biomedicine, encompassing proteomics, metabolomics, genomics/epigenomics, and transcriptomics, offers promising avenues for personalized medicine in allergy research. However, translating these basic research findings into clinical practice remains a challenge, necessitating further investigation to bridge this gap.
This research topic aims to explore the significant contributions of omic sciences to the field of allergy, focusing on their role in enhancing our understanding of the mechanisms involved in allergic reactions. The objective is to gather data that will be valuable from both clinical and basic immunology perspectives, with the ultimate goal of translating this information into clinical practice. By delving into the unique aspects of each type of allergic reaction, this research seeks to have a substantial impact on the fields of allergy and immunology.
To gather further insights in the application of omic sciences to allergic diseases, we welcome articles addressing, but not limited to, the following themes:
- Use of omic sciences in the study of allergic diseases.
- Biomarkers in drug, food, and respiratory allergic diseases.
- New insights into the mechanisms involved in allergic diseases.
- Revealing potential therapeutic targets in allergic diseases.
- Innovative diagnostic tools for allergic reactions.
- New experimental models that address the complexity of these diseases.
Keywords: allergy, omics, allergic, biomarkers
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
