Advancements in Percutaneous Coronary Intervention: Physiology and Intravascular Imaging Guidance

Percutaneous coronary intervention (PCI) has revolutionized the treatment of coronary artery disease, and recent advancements in physiological assessment and intravascular imaging have further enhanced its precision and outcomes.

This Research Topic aims to explore the latest innovations in PCI guided by physiological and imaging techniques, offering a comprehensive overview of their impact on clinical practice.

The integration of fractional flow reserve (FFR), instantaneous wave-free ratio (iFR), and other physiological measurements allows for more personalized treatment, ensuring that interventions are truly necessary and beneficial. Meanwhile, advances in intravascular imaging, including optical coherence tomography (OCT) and intravascular ultrasound (IVUS), provide detailed insights into plaque morphology and stent deployment, minimizing complications and optimizing procedural success.


We invite contributions that delve into:

1. Clinical Implementation and Outcomes:

o Studies evaluating the clinical outcomes of PCI guided by physiological and imaging methods.

o Comparative analyses of different physiological indices and imaging modalities.

2. Technological Developments:

o Innovations in imaging technologies and physiological assessment tools.

o Integration of artificial intelligence and machine learning in PCI guidance.

3. Case Studies and Reviews:

o Case reports demonstrating the real-world application of advanced imaging and physiology-guided PCI.

o Systematic reviews and meta-analyses summarizing current evidence.

4. Future Directions:

o Emerging trends in PCI guidance and potential future applications.

o Barriers to widespread adoption and strategies to overcome them.

By compiling these insights, this Research Topic seeks to advance the understanding and application of physiology and imaging-guided PCI, ultimately improving patient outcomes in cardiovascular care.