Upper urinary tract reconstruction (UUTR) and the management of ureteral strictures are crucial areas in urology that significantly impact patient health and quality of life. Ureteral strictures can develop from various causes, such as surgery, injury, infection, malignancy, or congenital issues. They can lead to complications like obstructive nephropathy and recurrent infections, which, if neglected, may escalate to renal failure. Developing a thorough understanding of the formation mechanisms, enhancing diagnostic procedures, and discovering innovative treatment options remain essential for improving patient outcomes.
This Research Topic aims to illuminate recent advancements in diagnosing and treating ureteral strictures and reconstructive practices for the upper urinary tract. We seek to explore the latest advancements, including pathological understandings, innovations in surgical techniques, and cutting-edge therapies, all of which are pivotal in evolving the standard of care for affected individuals.
To gather further insights into the complexities of ureteral strictures and upper urinary tract reconstruction, we welcome articles addressing, but not limited to, the following themes: •Molecular and cellular mechanisms leading to ureteral stricture formation, with a focus on inflammation, fibrosis, and muscle remodeling. •Innovations in imaging and biomarkers for early detection and progress monitoring of ureteral strictures. •Latest advancements in surgical methods, including minimally invasive and robotic surgeries, and graft or flap applications for reconstruction. •Application of regenerative medicine, tissue engineering, and scaffolds in ureteral healing and function restoration. •Exploration of new pharmacological treatments targeting fibrosis and scarring, including antifibrotic agents and gene therapies. •Utilization of 3D printing in tailored surgical planning, patient-specific models, and the development of ureteral scaffolds. •Strategies for optimizing post-operative care to enhance outcomes and minimize recurrence or complications.
Article types and fees
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
Brief Research Report
Clinical Trial
Curriculum, Instruction, and Pedagogy
Editorial
FAIR² Data
General Commentary
Hypothesis and Theory
Methods
Mini Review
Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.
Article types
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
