Inflammation and immune modulation induced by parasitic infection

Parasitic infections (helminths and protozoa) constitute a major public health concern in several regions worldwide, affecting millions of individuals and exerting a significant negative impact on both social and economic development. Parasites establish complex interactions with the host, leading to highly variable clinical outcomes. A deeper understanding of the mechanisms underlying self-limiting infections and disease progression remains a critical challenge, one that must be addressed to identify potential targets for novel pharmacological therapies and vaccine development.

The characteristics and intensity of the host's immune response to parasitic infection can lead to disease control or pathogenesis. The factors that determine host responses are variable and depend on the characteristics of both the host and the parasite. Therefore, it is necessary to elucidate the various facets of this relationship between the parasite and its hosts, as well as its outcomes.

As part of this Research Topic, we welcome the submission of original research, review, mini-review and other article types which focus on the following themes:

• Studies of the host-parasite relationship.
• Excretory and secretory products of parasites and their impact on the host.
• Host immune response to parasitic infection.
• Host immunomodulation by parasite.
• Therapeutic interventions and immunotherapy/vaccine development.
• Studies of the immunopathogenesis of parasitic infection.