Microwave Ablation in NSCLC: Expanding Multidisciplinary Horizons

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About this Research Topic

Submission deadlines

  1. Manuscript Summary Submission Deadline 15 March 2026 | Manuscript Submission Deadline 3 July 2026

  2. This Research Topic is currently accepting articles.

Background

Non-small cell lung cancer (NSCLC) remains the most prevalent type of lung cancer and a leading cause of cancer-related mortality worldwide. Surgical resection is the gold standard for early-stage NSCLC; however, not all patients are candidates due to factors like age, comorbidities, or poor pulmonary function. Recently, image-guided thermal ablation techniques, especially microwave ablation (MWA), have been recognized as viable minimally invasive alternatives for local tumor control. MWA shows distinct benefits, such as larger ablation volumes and shorter procedural times, reducing the heat-sink effect when compared to other thermal techniques. As the field of MWA continues to progress, there is a pressing need to integrate and assess its role within a broader multidisciplinary framework.

This Research Topic aims to investigate and enhance the clinical and scientific comprehension of microwave ablation in NSCLC management, accentuating the importance of a multidisciplinary approach. The efficacy of MWA in treating lung cancer relies on more than just technical expertise—it requires astute patient selection within a collaborative setting involving interventional radiologists, thoracic surgeons, pulmonologists, oncologists, and radiation specialists. This issue invites contributions that situate MWA within the larger scope of interdisciplinary care, illustrating how collaborative decision-making and tailored treatment strategies can optimize outcomes. We particularly seek studies on technical advancements, efficacy comparisons with other treatment methods, MWA’s role in multimodal therapy, and its application in cases of oligometastatic or recurrent disease. The goal is to facilitate cross-specialty communication to establish best practices and guide future endeavors in MWA adoption for NSCLC.

To gather further insights into the nuances of MWA in NSCLC, we welcome articles addressing, but not limited to, the following themes:

-Patient selection criteria and multidisciplinary decision-making in MWA
-Comparative effectiveness of MWA versus other ablative or surgical techniques
-Technical aspects and innovations in MWA procedure planning and execution
-Integration of MWA into multimodal therapy (e.g., chemotherapy, immunotherapy)
-The role of MWA in managing oligometastatic or recurrent NSCLC

We accept original research articles, clinical case reports, and comprehensive reviews on the aforementioned themes.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

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  • Editorial
  • FAIR² Data
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  • General Commentary
  • Hypothesis and Theory
  • Mini Review

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Keywords: thoracic surgery, NSCLC, lung cancer, microwave ablation, patient selection, multidisciplinary approach, COPD

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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