Animal Nutrition and Immunometabolism: From Basic Mechanisms to Sustainable Production

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About this Research Topic

Submission deadlines

  1. Manuscript Summary Submission Deadline 14 January 2026 | Manuscript Submission Deadline 4 May 2026

  2. This Research Topic is currently accepting articles.

Background

The intricate interplay between nutrition, immune function, and metabolic regulation forms the foundation of animal health, welfare, and productivity. The emerging field of immunometabolism has transformed our comprehension of how nutrients and metabolic pathways directly influence immune cell activation, fate, and function. In the realm of animal science, this shift underscores that nutrition transcends beyond mere energy fulfillment; it is a pivotal modulator of the immune system. Suboptimal nutrition can lead to metabolic dysregulation and increased susceptibility to disease, while strategic nutritional interventions can enhance immune resilience, improve metabolic efficiency, and reduce reliance on antibiotics. Understanding these mechanisms is essential for addressing global challenges in food security, animal welfare, and sustainable agricultural practices.



Our research topic focuses on shedding light on the molecular and physiological interactions among nutrition, immunity, and metabolism in animals. We aim to bridge the gap between fundamental science and practical applications, fostering innovations that enhance animal welfare, improve productivity, and promote sustainability. We are committed to spearheading a new era of "precision nutrition," in which dietary formulations are strategically designed to optimize immune and metabolic responses.



We invite submissions of Brief Research Report, Original Research, Review, Mini Review and Systematic Review. Topics of interest include, but are not limited to:



o The role of macro- and micronutrients (e.g., fatty acids, amino acids, vitamins, minerals) in modulating immune signaling pathways

o Metabolic reprogramming in immune cells during activation, inflammation, and resolution

o The gut microbiome as a mediator of nutritional immunometabolism

o Nutritional strategies to enhance disease resistance and vaccine efficacy

o The impact of metabolic disorders (e.g., obesity, ketosis) on immune competence

o Nutrigenomics and the molecular basis of nutrient-immune interactions

o Sustainable feed ingredients and their effects on immune-metabolic health

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

  • Brief Research Report
  • Case Report
  • Clinical Trial
  • Editorial
  • FAIR² Data
  • General Commentary
  • Hypothesis and Theory
  • Methods
  • Mini Review

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Keywords: Animals nutrition, Immunometabolism, Immune function, Metabolic regulation, Animal welfare, Precision nutrition

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Topic editors

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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