Helmet | List of Frontiers open access articles

Original Research

Published on 29 Jul 2025

Discovery of a selective dual-specificity tyrosine phosphorylation-regulated kinase 1B inhibitor with anti-adipogenic and anti-diabetic activities

in Experimental Pharmacology and Drug Discovery

Sein Kang
Yoon-Ju Na
Kyoung Jin Choi
Won Hoon Jung
Areum Park
Jeonghui Im
Sung Bum Park
Byumseok Koh
Joo-Youn Lee
Kwang-Lae Hoe

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1645033

392 views

Original Research

Published on 29 Jul 2025

CD2-targeted nanoparticles encapsulating IL-2 induce tolerogenic Tregs and TGF-β-producing NK cells that stabilize Tregs for long-term therapeutic efficacy in immune-mediated disorders

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

David A. Horwitz
Dongin Kim
Chang Kang
Katja Brion
Sean Bickerton
Antonio La Cava

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587237

439 views

Case Report

Published on 29 Jul 2025

Metastatic squamous cell carcinoma of mediastinal lymph nodes from the ileum: a case report and literature review

in Gastrointestinal Cancers: Colorectal Cancer

Yanan Zhang
Yumeng Yue
Zongxing Zhao
Haifeng Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1579029

234 views

Original Research

Published on 29 Jul 2025

Optimization method of electric vehicle energy system based on machine learning

in Engine and Automotive Engineering

Huanmei Ren

Frontiers in Mechanical Engineering

doi 10.3389/fmech.2025.1597558

442 views

Original Research

Published on 29 Jul 2025

Transient corundum stability in high-temperature metamorphic mineral assemblages: insights from the British Paleogene Igneous Province

in Petrology

Brian O’Driscoll
Hadrien Henry

Frontiers in Earth Science

doi 10.3389/feart.2025.1576938

431 views

Brief Research Report

Published on 29 Jul 2025

Hyporesponsive fetus-specific T cell responses in multiparous human pregnancy

in Immunological Tolerance and Regulation

Jessica C. Morgan
Grace E. Hynes
Jared M. Pollard
Michael S. Andrade
Jong Cheol Jeong
Anita S. Chong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634430

226 views

Original Research

Published on 29 Jul 2025

Cognitive and motor disturbances in depression: insights from comprehensive behavioral assessments

in Mood Disorders

Ioanna Douka
Marit F. L. Ruitenberg
Kamile Weischedel
Carlos Phouthavongsay
Sara L. Weisenbach
Jos N. van der Geest
Brian J. Mickey
Vincent Koppelmans

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1624776

287 views

Original Research

Published on 29 Jul 2025

The effects of Shenkang suppository on kidney function and gut microbiota in nondialysis patients with chronic kidney disease stages 3–4: A randomized controlled trial

in Renal Pharmacology

Weiwei Zhang
Xin Zhang
Shuang Xu
Yousuf Abdulkarim Waheed
Yizhou Xu
Shulin Li
Dong Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621208

298 views

Original Research

Published on 29 Jul 2025

A retrospective assessment of the implementation of virtual medical physics educational initiatives using the consolidated framework for implementation research

in Healthcare Professions Education

Noelle Fedor
E. Axel Abrahamson
Joseph Weygand

Frontiers in Medicine

doi 10.3389/fmed.2025.1625455

339 views

Original Research

Published on 29 Jul 2025

Forging partnerships for health equity research: transformative capacity-building for community-academic teams

in Public Health Education and Promotion

Carmen R. Valdez
Liana Petruzzi
Phillip W. Schnarrs
Tasha Banks
Chris M. Coombe
Barbara A. Israel

Frontiers in Public Health

doi 10.3389/fpubh.2025.1617711

274 views

Original Research

Published on 29 Jul 2025

Transcriptomic–proteomic analysis reveals the regulatory mechanisms of Alfalfa (Medicago sativa) in response to Fusarium acuminatum

in Plant Pathogen Interactions

Zhidan Shi
Hongxia Sun
Lifen Hao
Yongqing Yong
Chen Guo
Haiyan Huangfu
Hongli Huo
Lili Zhao
Jiuru Huangfu
Haijun Ding

Frontiers in Plant Science

doi 10.3389/fpls.2025.1620189

280 views

Review

Published on 29 Jul 2025

Sweroside: unveiling broad therapeutic potential—from mechanistic insights to clinical potential

in Ethnopharmacology

Liu Peng
Man Zuo
Tian Qiu
Wenying Lan
Yue Wen
Xiao-Qin Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594278

138 views

Original Research

Published on 29 Jul 2025

Mechanism of soil microbial community degradation under long-term tomato monoculture in greenhouse

in Microbial Symbioses

Menglu Li
Xiaobo Chen
Yushuang Cui
Xin Yue
Lianfen Qi
Yali Huang
Changxiong Zhu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1587397

417 views

Review

Published on 29 Jul 2025

The evolution of personalized stroke thrombectomy

in Neurosurgery

Emmanuel O. Mensah
Yew-Weng Fong
Sandeep Muram
Christopher S. Ogilvy
Philipp Tauskky

Frontiers in Surgery

doi 10.3389/fsurg.2025.1590146

649 views

Original Research

Published on 29 Jul 2025

Risk factors and long-term prognostic impact of immune related pancreatic injury in patients receiving immune checkpoint inhibitors

in Cancer Immunity and Immunotherapy

Yu Akazawa
Takuto Nosaka
Yosuke Murata
Tomoko Tanaka
Kazuto Takahashi
Tatsushi Naito
Masahiro Ohtani
Yasunari Nakamoto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590992

205 views

Original Research

Published on 29 Jul 2025

Divergent germination strategies of Phragmites australis seeds for tidal flat gradient adaptation and the implications for coastal wetland restoration

in Functional Plant Ecology

Peng Jia
Dezhi Li
Caifen Yu
Jing Jia
Jiangtao Wang
Ying Wang
Jing Chen

Frontiers in Plant Science

doi 10.3389/fpls.2025.1598379

261 views

Articles

Discovery of a selective dual-specificity tyrosine phosphorylation-regulated kinase 1B inhibitor with anti-adipogenic and anti-diabetic activities

CD2-targeted nanoparticles encapsulating IL-2 induce tolerogenic Tregs and TGF-β-producing NK cells that stabilize Tregs for long-term therapeutic efficacy in immune-mediated disorders

Metastatic squamous cell carcinoma of mediastinal lymph nodes from the ileum: a case report and literature review

Optimization method of electric vehicle energy system based on machine learning

Transient corundum stability in high-temperature metamorphic mineral assemblages: insights from the British Paleogene Igneous Province

Hyporesponsive fetus-specific T cell responses in multiparous human pregnancy

Cognitive and motor disturbances in depression: insights from comprehensive behavioral assessments

The effects of Shenkang suppository on kidney function and gut microbiota in nondialysis patients with chronic kidney disease stages 3–4: A randomized controlled trial

A retrospective assessment of the implementation of virtual medical physics educational initiatives using the consolidated framework for implementation research

Forging partnerships for health equity research: transformative capacity-building for community-academic teams

Transcriptomic–proteomic analysis reveals the regulatory mechanisms of Alfalfa (Medicago sativa) in response to Fusarium acuminatum

Sweroside: unveiling broad therapeutic potential—from mechanistic insights to clinical potential

Mechanism of soil microbial community degradation under long-term tomato monoculture in greenhouse

The evolution of personalized stroke thrombectomy

Risk factors and long-term prognostic impact of immune related pancreatic injury in patients receiving immune checkpoint inhibitors

Divergent germination strategies of Phragmites australis seeds for tidal flat gradient adaptation and the implications for coastal wetland restoration