Marginal Spectrum | List of Frontiers open access articles

Brief Research Report

Published on 27 Aug 2025

Analysis of head and neck cancer scRNA-seq data identified PRDM6 promotes tumor progression by modulating immune gene expression

in Cancer Immunity and Immunotherapy

Zhenyu Wu
Thurbu Tshering Lepcha
Dawei Zhou
Zhixian He
Guillaume N. Fiches
Youngmin Park
Jinshan He
Jianwen Chen
K. A. S. N. Shanaka
Steve Oghumu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596916

400 views

Original Research

Published on 27 Aug 2025

The efficacy of gasless endoscopic thyroidectomy via trans-subclavian approach in unilateral papillary thyroid carcinoma

in Thyroid Endocrinology

Xiangdang Yin
Jingyao Fu
Zhe Zhang
Rui Zhang
Zhaojun Li
Liyou Song
Tong Jin
Xudong Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1621481

440 views

Review

Published on 27 Aug 2025

New dimensions of PD-1/PD-L1 inhibitor combination therapy in cancer treatment: current advances and future perspectives

in Cancer Immunity and Immunotherapy

Cheng Tong
Yue Wu
Renzhao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616872

492 views

Case Report

Published on 27 Aug 2025

Case Report: Recurrent supraglottitis in a patient with metastatic melanoma treated with ipilimumab and nivolumab

in Skin Cancer

Marisa Palmeri
Sarah A. Weiss
Phillip Purnell

Frontiers in Oncology

doi 10.3389/fonc.2025.1615835

224 views

Original Research

Published on 27 Aug 2025

Role of the CX3CL1/CX3CR1 axis in iron metabolism and immune regulation during acute Trypanosoma cruzi infection

in Parasite Immunology

Sirlaine Pio
Tatiana Prata Menezes
Vitória Louise
Guilherme de Paula Costa
Daniel Malta Oliveira
Natiele Carlos
Silvia Paula-Gomes
Luiza Oliveira Perucci
André Talvani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585883

451 views

Original Research

Published on 27 Aug 2025

Correlation between serum ANCA and cancer: a decade-long retrospective analysis of an Italian cohort

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Enrico Brunetta
Lorenzo Del Moro
Marco Folci
Giacomo Ramponi
Davide Sacchet
Renato Alberto Sinico
Carlo Selmi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631498

290 views

Original Research

Published on 27 Aug 2025

Investigating serum iodine nutritional levels and their correlation with thyroid function in adult patients with Graves’ hyperthyroidism at different treatment stages

in Thyroid Endocrinology

Lilan Wang
Zixuan Ru
Shengnan Gao
Na Lv
Kerou Li
Hong Qiao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1628670

236 views

Review

Published on 27 Aug 2025

Therapeutic potential of TRIM family proteins in gastric cancer: from signaling pathway regulation to precision targeting strategies

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Caiqing Zhao
Jialing Qi
Zhenze Zhang
Qi Feng
Ziling Fang
Nian Fang

Frontiers in Oncology

doi 10.3389/fonc.2025.1628729

344 views

Case Report

Published on 27 Aug 2025

Case Report: The combination of upadacitinib and adalimumab in the treatment of refractory ankylosing spondylitis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jiajia Wu
Weiwei Wang
Xi Cheng
You Song
Xujing Yuan
Rong Du

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618725

286 views

Case Report

Published on 27 Aug 2025

Diagnostic pitfall in primary cervical gestational choriocarcinoma: a case report

in Gynecological Oncology

Jiayu Shi
Ping Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1608856

139 views

Review

Published on 27 Aug 2025

Metabolic disturbances in acute pancreatitis: mechanisms and therapeutic implications

in Systems Endocrinology

Chao Fang
Yingwei Ding
Xiaojun Wang
Xusheng Teng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1579457

447 views

Original Research

Published on 27 Aug 2025

CS Ratio is an immune-related prognostic biomarker for cervical cancer

in Gynecological Oncology

Peiqin Shi
Wenwen Zhang
Qingqing Yao
Zhanna Yuan
Jiaqi Wang
Ziye Yang
Pengpeng Qu

Frontiers in Oncology

doi 10.3389/fonc.2025.1547529

277 views

Methods

Published on 27 Aug 2025

From initiation of convective storms to their impact — the Swabian MOSES 2023 campaign in southwestern Germany

in Atmospheric Science

Jan Handwerker
Christian Barthlott
Matteo Bauckholt
Alexandre Belleflamme
Alexander Böhmländer
Erik Borg
Galina Dick
Peter Dietrich
Bernd Fichtelmann
Gernot Geppert

Frontiers in Earth Science

doi 10.3389/feart.2025.1555755

575 views

Case Report

Published on 27 Aug 2025

Case Report: Primary extraskeletal osteosarcoma in prostate

in Cancer Imaging and Image-directed Interventions

Youli Xu
Xing Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1558053

279 views

Original Research

Published on 27 Aug 2025

IFIT3 activation significantly contributes to HIV-1-associated neurodegenerative disorder-mediated neuroinflammation

in Viral Immunology

Ranjit Kumar Das
Nirakar Sahoo
Deepa Roy
Chun Xu
Jose Galarza
Maria Camila Mejia Garza
Hansapani Rodrigo
Asim K. Duttaroy
Upal Roy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532318

492 views

Original Research

Published on 27 Aug 2025

Targeting IL-6 receptor mediated metabolic pathways to control Th17 cell differentiation and inflammatory responses

in T Cell Biology

Yazan Alwarawrah
Amanda G. Nichols
Isha Patel
Andréa B. Ball
Nancie J. MacIver

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568514

278 views

Articles

Analysis of head and neck cancer scRNA-seq data identified PRDM6 promotes tumor progression by modulating immune gene expression

The efficacy of gasless endoscopic thyroidectomy via trans-subclavian approach in unilateral papillary thyroid carcinoma

New dimensions of PD-1/PD-L1 inhibitor combination therapy in cancer treatment: current advances and future perspectives

Case Report: Recurrent supraglottitis in a patient with metastatic melanoma treated with ipilimumab and nivolumab

Role of the CX3CL1/CX3CR1 axis in iron metabolism and immune regulation during acute Trypanosoma cruzi infection

Correlation between serum ANCA and cancer: a decade-long retrospective analysis of an Italian cohort

Investigating serum iodine nutritional levels and their correlation with thyroid function in adult patients with Graves’ hyperthyroidism at different treatment stages

Therapeutic potential of TRIM family proteins in gastric cancer: from signaling pathway regulation to precision targeting strategies

Case Report: The combination of upadacitinib and adalimumab in the treatment of refractory ankylosing spondylitis

Diagnostic pitfall in primary cervical gestational choriocarcinoma: a case report

Metabolic disturbances in acute pancreatitis: mechanisms and therapeutic implications

CS Ratio is an immune-related prognostic biomarker for cervical cancer

From initiation of convective storms to their impact — the Swabian MOSES 2023 campaign in southwestern Germany

Case Report: Primary extraskeletal osteosarcoma in prostate

IFIT3 activation significantly contributes to HIV-1-associated neurodegenerative disorder-mediated neuroinflammation

Targeting IL-6 receptor mediated metabolic pathways to control Th17 cell differentiation and inflammatory responses