Preclinical Stage | List of Frontiers open access articles

Original Research

Published on 01 Oct 2025

Combining immune-related adverse events and inflammatory profiles enhances prognostic accuracy in metastatic melanoma under PD-1-based therapy

in Cancer Immunity and Immunotherapy

Dionysios Garmpis
Guillermo Hidalgo-Gadea
Cornelia Mauch
Julia K. Tietze
Cindy Franklin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683533

363 views

Correction

Published on 01 Oct 2025

Correction: Advancements in antiviral approaches against foot-and-mouth disease virus: a comprehensive review

in Veterinary Infectious Diseases

Mahmoud Mohamadin
Rashid Manzoor
Ahmed Elolimy
Mohamed Abdelmegeid
Samah Mosad
Sahar Abd El Rahman

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1683089

491 views

Opinion

Published on 01 Oct 2025

Association of hormone replacement therapy and image-detected breast cancer

in Breast Cancer

Harry B. Burke

Frontiers in Oncology

doi 10.3389/fonc.2025.1647152

1,025 views

Original Research

Published on 01 Oct 2025

Critical appraisal of studies evaluating prevalence of attention deficit hyperactivity disorder

in ADHD

Michelle Tivadar
Sara Popit
Igor Locatelli
Matej Stuhec

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1646618

2,162 views

Original Research

Published on 01 Oct 2025

Comparative outcomes of operable non-inflammatory and non-metastatic inflammatory breast cancer in Morocco: a retrospective cohort study

in Breast Cancer

Nabil Ismaili
Fadila Guessous
Sanaa El Majjaoui

Frontiers in Oncology

doi 10.3389/fonc.2025.1642650

524 views

Opinion

Published on 01 Oct 2025

Macrophage subtypes and pathways in autoimmune interstitial lung diseases: potential therapeutic targets

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Richa Tyagi
Surya Kant

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638345

312 views

Original Research

Published on 01 Oct 2025

Analysis of the predictive value of red cell distribution width (RDW) and hemoglobin-to-RDW ratio (HRR) on the prognosis of patients undergoing total laryngectomy

in Head and Neck Cancer

Zhixuan Fang
Kai Niu

Frontiers in Oncology

doi 10.3389/fonc.2025.1651738

816 views

Original Research

Published on 01 Oct 2025

Artemisia argyi essential oil modulates lipid metabolism via linoleic acid and glycerophospholipid pathways in high-fat diet-induced obese mice

in Nutritional Immunology

Kaijun Wang
Anqi Yang
Yunxia Li
Qi Han
Zhangzheng Yin
Siting Xia
Jiayi Chen
Jiahao Mo
Peng Bin

Frontiers in Nutrition

doi 10.3389/fnut.2025.1650976

580 views

Opinion

Published on 01 Oct 2025

Combined with multimodal medical imaging and artificial intelligence for early diagnosis of Parkinson's disease

in Artificial Intelligence in Neurology

Sitong Lu
Shuang Gui
Chunyun Wang
Yu Liu

Frontiers in Neurology

doi 10.3389/fneur.2025.1650968

829 views

Original Research

Published on 01 Oct 2025

Increased levels of ficolin-1 and of C3dg are independently associated with high risk of infection in patients with chronic kidney disease: a prospective cohort study

in Molecular Innate Immunity

Solbjørg Sagedal
Markus Hovd
Anders Åsberg
Tom Eirik Mollnes
Olav Klingenberg
Torbjørn Fossum Heldal
Bartlomiej J. Witczak
Trine Korsgaard Hejlesen
Anne Troldborg
Steffen Thiel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645347

583 views

Review

Published on 01 Oct 2025

Mechanism and application of injectable hydrogel as carrier system in the treatment of osteoarthritis

in Biomaterials

Bing-Gang Zhang
Qiang Liu
Tao Ma
Jian-Jun Liu
Yan Zhang
Fang Liu
Xiao-Ming Wen
Duo-Xian Wang
Wei Jiang
Wen-Bo An

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1636518

527 views

Original Research

Published on 01 Oct 2025

Conditions for perfect transmission of quantum particles across layered heterostructures and resonance effects of an auxiliary well potential

in Mathematical Physics

Yaroslav Zolotaryuk
Alexander V. Zolotaryuk

Frontiers in Applied Mathematics and Statistics

doi 10.3389/fams.2025.1636414

542 views

Original Research

Published on 01 Oct 2025

Proliferation and metabolic activity of the Atlantic sturgeon cell line AOXlar7y under short-term serum-reduced conditions, and the effect of stimulation with growth factors and cytokines

in In Vitro Toxicology

Valeria Di Leonardo
Julia Brenmoehl
Heike Wanka
Bianka Grunow

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636776

606 views

Original Research

Published on 01 Oct 2025

Bactericidal activity of ceragenin CSA-13, CSA-44 and CSA-131 against bacteria causing bloodstream infections

in Antimicrobials, Resistance and Chemotherapy

Angelika Mańkowska
Paulina Paprocka
Łukasz Suprewicz
Agata Lesiak
Kamila Fortunka
Grzegorz Król
Jakub Spałek
Sławomir Okła
Bonita Durnaś
Tamara Daniluk

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1640392

506 views

Original Research

Published on 01 Oct 2025

Comprehensive assessment of heavy metal pollution in northeast Fuqing Bay: integrating sediments, seawater, and marine organisms analysis with multivariate techniques

in Coastal Ocean Processes

Enkang Wang
Yongchao Yang
Yonggen Sun
Jing Wang
Xuanbo Chen
Jiaojiao Yang
Jianqiang Wang
Chao Dong
Jiandong Qiu
Zhao Wang

Frontiers in Marine Science

doi 10.3389/fmars.2025.1684021

676 views

Original Research

Published on 01 Oct 2025

METTL3-mediated activation of Sonic Hedgehog signaling promotes breast cancer progression

in Cellular Biochemistry

Sunanda Baidya
Utpal Barua
Muntasim Rahman Shanto
Tayeba Sultana Sonia
Md. Al Amin
Saima Sultana
Nusrat Jerin
Khadiza Jahan
Israt Jahan
Shakera Ahmed

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1674339

1,874 views

Articles

Combining immune-related adverse events and inflammatory profiles enhances prognostic accuracy in metastatic melanoma under PD-1-based therapy

Correction: Advancements in antiviral approaches against foot-and-mouth disease virus: a comprehensive review

Association of hormone replacement therapy and image-detected breast cancer

Critical appraisal of studies evaluating prevalence of attention deficit hyperactivity disorder

Comparative outcomes of operable non-inflammatory and non-metastatic inflammatory breast cancer in Morocco: a retrospective cohort study

Macrophage subtypes and pathways in autoimmune interstitial lung diseases: potential therapeutic targets

Analysis of the predictive value of red cell distribution width (RDW) and hemoglobin-to-RDW ratio (HRR) on the prognosis of patients undergoing total laryngectomy

Artemisia argyi essential oil modulates lipid metabolism via linoleic acid and glycerophospholipid pathways in high-fat diet-induced obese mice

Combined with multimodal medical imaging and artificial intelligence for early diagnosis of Parkinson's disease

Increased levels of ficolin-1 and of C3dg are independently associated with high risk of infection in patients with chronic kidney disease: a prospective cohort study

Mechanism and application of injectable hydrogel as carrier system in the treatment of osteoarthritis

Conditions for perfect transmission of quantum particles across layered heterostructures and resonance effects of an auxiliary well potential

Proliferation and metabolic activity of the Atlantic sturgeon cell line AOXlar7y under short-term serum-reduced conditions, and the effect of stimulation with growth factors and cytokines

Bactericidal activity of ceragenin CSA-13, CSA-44 and CSA-131 against bacteria causing bloodstream infections

Comprehensive assessment of heavy metal pollution in northeast Fuqing Bay: integrating sediments, seawater, and marine organisms analysis with multivariate techniques

METTL3-mediated activation of Sonic Hedgehog signaling promotes breast cancer progression