Corrigendum: Transcriptomic Profiling of Zebrafish Hair Cells Using RiboTag

Although the reported fold change values and statistics were accurate, there was a mistake in the CPM values shown in Supplementary Dataset 1 in the original article. This mistake has been corrected and it has resulted in a slight change in the number of transcripts meeting the CPM cutoff for expression (n = 17,164), enrichment (n = 2,379), and depletion (n = 2,258). These corrected numbers of expressed, enriched and depleted transcripts are now reflected in the text, as well as in Figure 3a. The gene ontology and ZEOGS analyses have been redone and changes have been made to Tables 1–3, and Supplementary Table 2. The genes chosen for validation now fall within the top 100 enriched transcripts rather than the top 50; therefore, Supplementary Table 3 has been changed to show the top 100 enriched transcripts. The scientific conclusions made from these analyses have not changed in any way.

Figure 3

A fourth input sample, which was included in the original analysis, was missing from Supplementary Dataset 1 and Supplementary Table 1 in the original article. This sample has now been added to both the files. Sentence one in the subsection “RNA sequencing and informatics” under “Materials and Methods”, now reads “RNA from 5 dpf Tg (myo6b:RiboTag) zebrafish IN and IP samples was submitted in biological quadruplicates for RNA-Seq at the UMSOM Institute for Genome Sciences.” The following sentence has also been added: “One IP sample had a high intergenic content suggestive of DNA contamination and was excluded from the analysis.” Finally, sentence two in paragraph one of the subsection “RNA sequencing of IP and IN samples from Tg(myo6b:RiboTag) zebrafish” under “Results”, now reads “We therefore performed RNA-Seq on IP and IN samples in at least three biological replicates from 5 dpf Tg(myo6b:RiboTag) zebrafish”.

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way.

The original article has been updated.

Statements

Summary

Keywords

inner ear, hair cells, zebrafish, RiboTag, RNA-Seq

Citation

Matern MS, Beirl A, Ogawa Y, Song Y, Paladugu N, Kindt KS and Hertzano R (2018) Corrigendum: Transcriptomic Profiling of Zebrafish Hair Cells Using RiboTag. Front. Cell Dev. Biol. 6:84. doi: 10.3389/fcell.2018.00084

Received

06 June 2018

Accepted

17 July 2018

Published

27 August 2018

Volume

6 - 2018

Edited and reviewed by

Kelvin Y. Kwan, Rutgers University, The State University of New Jersey, United States

Updates

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Copyright

© 2018 Matern, Beirl, Ogawa, Song, Paladugu, Kindt and Hertzano.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Ronna Hertzano rhertzano@som.umaryland.edu

This article was submitted to Epigenomics and Epigenetics, a section of the journal Frontiers in Cell and Developmental Biology

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