BRIEF RESEARCH REPORT article
Speech Rate Adjustments in Conversations With an Amazon Alexa Socialbot
- 1Phonetics Lab, University of California, Davis, CA, United States
- 2Natural Language Processing Lab, University of California, Davis, CA, United States
- 3Department of Computer Science, Columbia University, New York, NY, United States
This paper investigates users’ speech rate adjustments during conversations with an Amazon Alexa socialbot in response to situational (in-lab vs. at-home) and communicative (ASR comprehension errors) factors. We collected user interaction studies and measured speech rate at each turn in the conversation and in baseline productions (collected prior to the interaction). Overall, we find that users slow their speech rate when talking to the bot, relative to their pre-interaction productions, consistent with hyperarticulation. Speakers use an even slower speech rate in the in-lab setting (relative to at-home). We also see evidence for turn-level entrainment: the user follows the directionality of Alexa’s changes in rate in the immediately preceding turn. Yet, we do not see differences in hyperarticulation or entrainment in response to ASR errors, or on the basis of user ratings of the interaction. Overall, this work has implications for human-computer interaction and theories of linguistic adaptation and entrainment.
After their introduction in the 2010s, there has been a widespread adoption of voice-activated artificially intelligent (voice-AI) assistants (e.g., Google Assistant, Amazon’s Alexa, Apple’s Siri), particularly within the United States (Bentley et al., 2018). Millions of users now speak to voice-AI to complete daily tasks (e.g., play music, turn on lights, set timers) (Ammari et al., 2019). Given their presence in many individuals’ everyday lives, some researchers have aimed to uncover the cognitive, social, and linguistic factors involved in voice-AI interactions by examining task-based interactions with voice-AI (e.g., setting an appointment on a calendar in Raveh et al., 2019), scripted interactions in laboratory settings (Cohn et al., 2019; Zellou et al., 2021), and interviews to probe how people perceive voice-AI (Lovato and Piper, 2015; Purington et al., 2017; Abdolrahmani et al., 2018). Yet, our scientific understanding of non-task based, or purely social, interactions with voice-AI is even less established.
Since 2017, the Amazon Alexa Prize competition has served as a venue for social chit-chat between users and Amazon Alexa socialbots on any Alexa-enabled device; with a simple command, “Alexa, let’s chat”, any user can talk to one of several university-designed socialbots (Chen et al., 2018; Ram et al., 2018; Gabriel et al., 2020; Liang et al., 2020). Do individuals talk to these socialbots in similar ways as they do with real humans? The Computers are Social Actors (CASA; Nass et al., 1997; Nass et al., 1994) framework proposes that people apply socially mediated, ‘rules’, from human-human interaction to computers when they detect a cue of ‘humanity’ in the system. Voice-AI systems are already imbued with multiple human-like features: they have names, apparent genders Habler et al. (2019) and interact with users using spoken language. Indeed, there is some evidence that individuals engage with voice-AI in ways that parallel the ways they engage with humans (e.g., gender-asymmetries in phonetic alignment in Cohn et al., 2019; Zellou et al., 2021). In the case of voice-AI socialbots, the cues of humanity could be even more robust since the system is designed for social interaction.
To uncover some of the cognitive and linguistic factors in how users perceive voice-AI socialbots, the current study examines two speech behaviors: ‘hyperarticulation’ and ‘entrainment’. We define ‘hyperarticulation’ as carefully articulated speech (also referred to as ‘clear’ speech; Smiljanić and Bradlow, 2009), thought by listener-oriented accounts to be tailored specifically to improve intelligibility for an interlocutor in the conversation (Lindblom, 1990). For example, there is a body of work examining acoustic adjustments speakers make when talking to computer systems, or ‘computer-directed speech’ (computer-DS) (Oviatt et al., 1998a; Oviatt et al., 1998b; Bell and Gustafson, 1999; Bell et al., 2003; Lunsford et al., 2006; Stent et al., 2008; Burnham et al., 2010; Mayo et al., 2012; Siegert et al., 2019). A common listener-oriented hyperarticulation is to slow speaking rate, produced in response to background noise (Brumm and Zollinger, 2011), as well as in interactions with interlocutors assumed to be less communicatively competent, such as computers (Oviatt et al., 1998b; Stent et al., 2008), infants (Fernald and Simon, 1984), and non-native speakers (Scarborough et al., 2007; Lee and Baese-Berk, 2020). Will users also slow their speech rate when they talk to a socialbot? One possibility that the advanced speech capabilities in Alexa socialbots (in terms of speech recognition, language understanding and generation) might lead to more naturalistic interactions, whereby users talk to the system more as they would an adult human interlocutor. Alternatively, there is work showing that listeners rate ‘robotic’ text-to-speech (TTS) voices as less communicatively competent than more human-like voices (Cowan et al., 2015) and that listeners perceive prosodic peculiarities in the Alexa voice, describing it as being ‘monotonous’ and ‘robotic’ (Siegert and Krüger, 2020). Accordingly, an alternative prediction is that speakers will use a slower speaking rate when talking to the Alexa socialbot, since robotic voices are perceived as being less communicatively competent.
In addition to hyperarticulation, we examine ‘entrainment’ (also known as ‘accommodation’, ‘alignment’, or ‘imitation’): the tendency for speakers to adopt their interlocutor’s voice and language patterns. For example, a speaker might increase their speech rate in response to hearing the socialbot’s speech rate increase. Entrainment has been previously observed both in human-human (Levitan and Hirschberg, 2011; Babel and Bulatov, 2012; Lubold and Pon-Barry, 2014; Levitan et al., 2015; Pardo et al., 2017) and human-computer interaction (Coulston et al., 2002; Bell et al., 2003; Branigan et al., 2011; Fandrianto and Eskenazi, 2012; Thomason et al., 2013; Cowan et al., 2015; Gessinger et al., 2017; Gessinger et al., 2021), suggesting it is a behavior transferred to interactions with technology. Recent work has shown that entrainment occurs in interactions with voice-AI assistants as well (Cohn et al., 2019; Raveh et al., 2019; Zellou et al., 2021). Like hyperarticulation, there are some accounts proposing that entrainment improves intelligibility (Pickering and Garrod, 2006), aligning representations between interlocutors. For example, people entrain toward the lexical and syntactic patterns of computers, lessening (presumed) communicative barriers (Branigan et al., 2011; Cowan et al., 2015). At the same time, entrainment can also reveal social attitudes: social accounts of alignment propose that people converge to convey social closeness and diverge to signal distance (Giles et al., 1991; Shepard et al., 2001), such as entraining more to interlocutors they like (Chartrand and Bargh, 1996; Levitan et al., 2012). In the current study, we predict that speakers who rate the socialbot more positively will also show more entrainment toward it.
While the vast majority of prior work examines hyperarticulation and entrainment separately (e.g., Burnham et al., 2010; Cohn et al., 2019), the current study models these behaviors in tandem. This is important as hyperarticulation and entrainment might both result in the same observed behavior: a speaker might speak slower when talking to the socialbot overall (hyperarticulation), but also slow in response to a slower speech rate by the bot (entrainment). Including both in the same model allows us to attribute observed behavior to its underlying cognitive processes. This is also important as hyperarticulation and entrainment might, at times, conflict (e.g., slowing overall speech rate, but entraining to the faster rate of the bot). Additionally, including both measures in the same model can directly test the extent hyperarticulation and entrainment are mediated by functional pressures (e.g., speech recognition errors) and social-situational pressures (e.g., presence of an experimenter).
Functional Factors in Hyperarticulation and Entrainment
How might hyperarticulation and entrainment vary as a function of intelligibility pressures that change dynamically within a conversation? Automatic speech recognition (ASR) mistakes are common in a spontaneous interaction with a voice-AI system. The present study investigates whether turn-by-turn dynamics of hyperarticulation and entrainment vary based on whether the Alexa system makes a comprehension error or not. There is a rich literature examining hyperarticulation toward computer interlocutors in response to an error made by the system (Oviatt and VanGent, 1996; Oviatt et al., 1998b; Bell and Gustafson, 1999; Swerts et al., 2000; Vertanen, 2006; Stent et al., 2008; Maniwa et al., 2009; Burnham et al., 2010). For example, Stent et al. (2008) found that speakers’ increased hyperarticulation in response to an ASR error lingered for several trials before ‘reverting’ back to their pre-error speech patterns; in the present study, we similarly predict slower speech rate following an ASR error. While less examined than hyperarticulation, there is some evidence suggesting that entrainment also serves a functional role (Branigan et al., 2011; Cowan et al., 2015); for example, participants show more duration alignment if their interlocutor made an error (Zellou and Cohn, 2020). Thus, we might also predict greater entrainment following an error, relative to pre-error.
Situational Factors in Hyperarticulation and Entrainment
How might context shape speech hyperarticulation and entrainment toward an Alexa socialbot? In the current study, half of the participants interacted with the socialbot in-person in a laboratory setting with experimenters present, while the other half interacted at home1 using the Amazon Alexa app. While many studies of voice-AI are conducted in a laboratory setting (e.g., Cohn et al., 2019; Zellou et al., 2021), there is evidence that the presence of an experimenter influences how participants complete a task (Orne, 1962; Belletier et al., 2015; Belletier and Camos, 2018). Indeed, Audience Design theory proposes that people tailor their speech style for their intended addressee, as well as for ‘overhearers’ (i.e., individuals listening to the conversation, but not directly taking part) (Clark and Carlson, 1982). For example, speakers are more polite when there is a bystander present (Comrie, 1976). As a result, we might predict more careful, hyperarticulated speech in a lab setting with overhearers. Prior work has also shown that engaging with additional interlocutors shapes entrainment: Raveh et al. (2019) found that speakers entrained less toward an Alexa assistant if they had interacted with a third interlocutor (a human confederate), compared to dyadic interactions only between the user and Alexa. Therefore, we might predict that participants will display less entrainment in the laboratory setting (relative to at-home).
In the current study, we use a socialbot system originally designed for Amazon Alexa Prize (Chen et al., 2018; Liang et al., 2020). In-lab user studies were conducted on the same day (pre-social isolating measures) in a quiet room. At-home user studies occurred across nine days in April-June, where speakers participated in an online experiment, activating the socialbot from home and recording their interaction with their computer microphone in a quiet room.
Participants (n = 35) were native English speakers, recruited from UC Davis (mean age = 20.94 years old ±2.34; age range 18–30 years; 22 female, 13 male). The in-lab user condition, consisting of 17 participants (mean age = 20.76 years ±2.66; 14 female, 3 male). An additional 18 participants (mean age = 21.11 years ±2.03, 9 female, 9 male) completed an at-home user condition. A t-test revealed that there was no significant difference in ages between these groups [t (29.9) = −0.43, p = 0.67]. Nearly all participants (34/35) reported using voice-AI assistants in the past. All participants consented to the study (following the UC Davis Institutional Review Board) and received course credit for their participation.
In-lab participants completed the experiment in a quiet room, with an Amazon Echo located in front of them on a table. Their interactions were recorded using a microphone (Audio-Technica AT 2020) facing the participant. An experimenter initiated the socialbot, and 1-2 experimenters were present in the room to listen to the conversation. Those in the at-home condition completed the experiment online via a Qualtrics survey which was used to record their speech (via AddPipe2 and their computer microphone). For the at-home condition, participants were given instructions to install the Alexa app to their phones and activate a Beta version of the socialbot.
All participants began with a baseline recording of an utterance: “The current month is [current month]. Test of the sound system complete.” Then, they initiated the socialbot conversation and were instructed to have two conversational interactions with the system for roughly 10 min each (see Table 1 for an example excerpt). If the bot crashed before the 10 min, they were asked to re-engage the Alexa Skill again. Dialogue flows included multiple domains (e.g., movies, sports, animals, travel, food, music, and books), as well as general chit-chat and questions about Alexa’s ‘backstory’ (e.g., favorite color, animal, etc.) (Chen et al., 2018; Liang et al., 2020). At the end of the interaction, participants rated the Alexa socialbot across three dimensions, on a scale of 1–5: “How engaging did you find the bot? 1 = not engaging, 5 = extremely engaging”, “How likely would you talk to the bot again? 1 = not likely, 5 = extremely likely”, “How coherent was the bot? 1 = not coherent, 5 = extremely coherent”.
Baseline and conversation recordings were initially transcribed with Amazon ASR or Sonix3. Trained research assistants confirmed the accuracy of the transcripts and annotated the sound files in a Praat Textgrid (Boersma and Weenink, 2018), labeling the interlocutor turns and the presence of ASR errors made by the socialbot. Errors included ‘long pause’ errors, such as when the socialbot took a long pause and then used an interjection or responded with phrases like “Tik tok! Did I confuse you?” or “Are you still there?” Other ASR errors included when the socialbot responded with a different word or topic than what the user mentioned. For instance, when the user said they were watching tv shows recently, the socialbot responded with “Great! I love talking about sports … ”
We analyze only the first continuous conversation with Alexa in order to assess differences from baseline to the bot interaction, rather than differences between bot conversations. On average, participants spoke with the socialbot for 12.48 min (sd = 5.44) including 96.63 total turns (user + Alexa) (sd = 44.58). The socialbot made an average of 6.94 errors per conversation (sd = 5.57). T-tests confirmed no difference in conversation duration [t (29.52) = −1.03, p = 0.31], overall number of turns [t (29.58) = −0.90, p = 0.37], or number of errors [t (23.49) = −0.23, p = 0.82] across in-lab and at-home contexts. In total, the corpus consisted of 1,417 productions by the human users.
Speech rate (mean number of syllables per second) was measured using a Praat script (De Jong et al., 2017) for each of the socialbot’s turns, user’s turns, and the user’s baseline productions. To measure differences in hyperarticulation in talking to the Alexa socialbot, we centered each user’s turn-level speaking rate relative to their baseline production (i.e., subtracting all ‘speech rate’ values by the user’s average baseline speech rate). This centered value is then used to ascertain change from a user’s baseline. For instance, a positive value indicates an increase in speaking rate from baseline.
To measure entrainment, we test ‘synchrony’ (Coulston et al., 2002; Levitan & Hirschberg, 2011): how speakers synchronize their productions across turns. For instance, when the Alexa produces a relatively faster speaking rate, does the user also show a relative increase in speaking rate? We used the user’s turn-level rate measurements (centered within user) and also centered the Alexa’s productions (subtracting the mean speaking rate of Alexa’s overall values for each conversation). Accordingly, comparing the ‘Alexa-prior turn’ (centered) and user’s value (centered) can capture whether users adjust their speech to match the directionality of change. Additionally, this method allows us to compare both hyperarticulation and entrainment in the same model, with the dependent variable of the (centered) user’s speaking rate.
Statistical Analysis and Results
A t-test revealed that the Alexa was rated as more engaging in the at-home condition (mean = 4.10) relative to the in-lab condition (mean = 3.35) [t (31.84) = 2.52, p < 0.05]. There was no significant difference in ratings of how coherent the bot was [t (30.52) = 0.83, p = 0.41] or in how much the participant would want to talk to the bot again [t (30.01) = −1.52, p = −0.14] based on situational context. We calculated an overall ratings value, summing users’ ratings for engagement, coherence, and desire to talk to the bot again (mean = 11.30, range = 7–14) to use in the statistical model on speaking rate change.
Users’ Baseline Productions and Alexa Productions Across Context
Mean values for speaking rate of the user’s baseline productions, users’ responses to the socialbot, as well as the socialbot’s productions are provided in Table 2. As seen, there were differences in the baseline productions based on setting, where speakers produced slower rate in-lab in their baseline production. The Alexa productions had a faster speech rate in-lab (relative to at-home)4.
Hyperarticulation and Entrainment
We modeled speech rate (centered within user) with a linear mixed effects model using the lme4 R package (Bates et al., 2015). Fixed effects included Setting (2 levels: in-lab, at-home), Overall Rating (coherence + satisfaction + engagement, centered), and all possible two-way interactions with Alexa Prior Turn Rate (continuous, centered). We additionally added Gender as a fixed effect (2 levels: female, male)5. Random effects included by-User random intercepts6. Categorical contrasts were sum coded.
The model showed a significant negative intercept, indicating that users’ speaking rate decreases (i.e., fewer syllables/second) in the socialbot interactions relative to baseline productions [Coef = −0.62, t = −5.96, p < 0.001]. Additionally, there was a main effect of Setting, shown in Figure 1: speakers produced an even slower speech rate in-lab, relative to at-home [Coef = −0.37, t = −3.59, p < 0.01]. Furthermore, there was an effect of Gender: female users slowed their speech rate even more during socialbot interactions [Coef = −3.18, t = −2.95, p < 0.01].
FIGURE 1. Speech rate change (relative to the user’s baseline, 0.0; centered) across the at-home and in-lab settings. A decrease in the number of syllables/second (a more negative number) indicates a slower speech rate. Error bars depict standard error.
There was also an effect of Alexa Prior Turn Rate: user’s speech rate increases when the speech rate increases in the Alexa Prior Turn [Coef = 5.61, t = 11.90, p < 0.001] (see Figure 2). There was no observed effect of Overall Rating and no interactions observed.
FIGURE 2. Speech rate change (centered relative to the user’s baseline) across the at-home and in-lab settings. A decrease in the number of syllables/second (a negative number) indicates a slower speech rate. Shading depicts the standard error.
Hyperarticulation and/or Entrainment After an Automatic Speech Recognition Error?
We analyzed speaker’s speech rate in a subset of the data consisting of the four user turns preceding an ASR error (Pre-Error) and four turns following an ASR error (Post-Error) (n = 771 turns, n = 327 users). Rate (centered) was modeled with a linear mixed effects model. Fixed effects included Error Condition (pre-error, post-error), Setting (in-lab, at-home), their interaction, and Gender (female, male)8, and by-User random intercepts. Contrasts were sum coded.
The model revealed a similar effect in the Pre- and Post-error subset as in the main model: an overall negative intercept [Coef = −0.71, t = −6.88, p < 0.001], an effect of Setting [Coef = 0.44 t = −4.45, p < 0.001], Alexa Prior Turn [Coef = 0.57, t = 7.91, p < 0.001], as well as Gender [Coef = −0.36, t = −3.55, p < 0.01]. However, there were no effects of Error Condition and no interactions including Error Condition observed.
This study examined users’ speech rate hyperarticulation and entrainment toward an Amazon Alexa socialbot in a conversational interaction. While generally tested and analyzed separately (e.g., Burnham et al., 2010; Cohn et al., 2019), this study highlights the importance of accounting for both hyperarticulation and entrainment to provide a fuller picture of speech interactions with voice-AI/computer interlocutors.
First, we find evidence of hyperarticulation: relative to their original baseline productions, users consistently decrease their speech rate when talking to the socialbot. This supports listener-centered accounts: speakers produce ‘clearer’ speech for listeners who might have trouble understanding them (Lindblom, 1990; Smiljanić and Bradlow, 2009). Indeed, these findings are consistent with slower speech rate observed for interlocutors presumed to have communicative difficulties, such as dialogue systems that have higher error rates (Oviatt et al., 1998b; Stent et al., 2008), as well as infants and non-native speakers (Fernald and Simon, 1984; Scarborough et al., 2007).
Above and beyond the hyperarticulation effect, we also find evidence for turn-level entrainment toward the speech rate patterns of the social bot. If Alexa produces a faster speech rate, users are more likely to speed up in the subsequent turn; conversely, if Alexa’s speech rate slows, users also slow their rate in the subsequent turn. This is consistent with prior findings in entrainment toward computers (e.g., amplitude convergence toward computer characters in Coulston et al., 2002). Yet, we did not find evidence that entrainment was linked to social ratings of the interaction, as is proposed by some alignment accounts (Giles et al., 1991; Shepard et al., 2001). One possibility is that socially mediated pressures differently affect entrainment toward voice-AI and humans in non-task oriented interactions (here, social chit-chat), but might do so in more task-oriented interactions (e.g., in a tutoring task in Thomason et al., 2013) or in less socially rich contexts (e.g., single word shadowing in (Cohn et al., 2019; Zellou et al., 2021). Another possibility is that the range of ratings might have been too narrow to detect a difference (if present), where the majority of speakers rated the interactions favorably. Future work exploring whether social sentiments influence entrainment toward socialbots can elucidate these questions.
Furthermore, we also observed differences in speech rate hyperarticulation by context: users slowed down even more in conversations in-lab than at-home. This is consistent with our prediction that participants would produce more careful, ‘clear’ speech when other observers were present—and is in line with Audience Design theory (Clark and Carlson, 1982) that productions are also tailored based on ‘overhearers’. Still, we cannot conclusively point to the overhearer as the source of this effect; it is possible that this reflects that the in-lab condition participants produced faster speech in their baseline (averaging ∼4 syllables/sec) and, possibly, had more room to hyperarticulate (slowing to an average of 2.93 syllables/sec). Future work parametrically manipulating speech rate—as well as comparing the same participants both in-lab and at-home can further tease apart these possibilities.
In addition to examining situational context, we also tested the impact of functional pressures in communication—specifically whether speakers hyperarticulate and/or entrain more following a system ASR error. We did not find effects for either behavior, contra findings human-computer interaction for post-error hyperarticulation (e.g., Oviatt et al., 1998b; Vertanen, 2006) or post-error entrainment (Zellou and Cohn, 2020). One possible explanation for why we do not observe hyperarticulation following ASR errors is that speakers were already talking in a very slow, ‘clear speech’ manner when talking to the socialbot. This explanation is consistent with studies in which, at a higher error rate, speakers maintain hyperarticulation (Oviatt et al., 1998b; Stent et al., 2008).
There were also limitations in the present study that can serve as the basis for future research. One such limitation is that we had different participants in the in-lab and at-home conditions; while one benefit to this approach was that the interaction consisted of the first socialbot conversation each user had with the system, future work examining user speech across different contexts can further tease apart the source of differences observed across settings. Furthermore, we observed differences by gender, where female participants slowed their speech even more to the socialbot; yet, as the current study was not balanced by gender, future work is needed to test whether this difference is truly socially mediated—with more hyperarticulation produced by females (e.g., increased pitch range by females in Oviatt et al., 1998b)—or possibly driven by the individual speakers in the study. Additionally, here we test one socialbot system; future work testing other systems can shed more light on how users hyperarticulate and entrain toward socialbots, more generally.
Overall, this study contributes to our broader scientific understanding of human and voice-AI interaction. Here, we find that speakers use hyperarticulation and entrainment in speech interactions with an Alexa socialbot, paralleling some patterns observed in human-human interaction. Future work directly testing a human vs. socialbot interlocutor comparison can further tease apart possible differences in social interactions with the two types of interlocutors. Additionally, human-human conversational entrainment is coordinative, with each speaker adapting their output (Levitan et al., 2015; Szabó, 2019). There is some work investigating the effects of adapting TTS output to entrain toward the user (Lubold et al., 2016). Future studies examining the extent to which speakers entrain to Alexa socialbots—as they entrain to the user—can shed light on the situational, functional, and interpersonal dynamics of human-socialbot interaction.
Data Availability Statement
The datasets presented in this article are not readily available because participants cannot be deidentified in their conversations with the socialbot. Requests to access the datasets should be directed to email@example.com.
The studies involving human participants were reviewed and approved by UC Davis Institutional Review Board (IRB). The participants provided their written informed consent to participate in this study.
MC and K-HL contributed to the conception and design of the study. K-HL developed the socialbot with ZY. MC and MS led the acoustic analysis and received feedback from GZ. MC wrote the first draft of the manuscript. All authors contributed to the editing and revision of the manuscript.
This material is based upon work supported by the National Science Foundation SBE Postdoctoral Research Fellowship under Grant No. 1911855 to MC, an Amazon Faculty Research Award to GZ, and the Amazon Alexa Prize competition in supporting the bot development to ZY and KL. The funders were not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication.
Conflict of Interest
The authors declare that this study received funding from Amazon.
1Due to the COVID-19 pandemic, all in-lab user studies were paused in Spring 2020.
4Differences in the social bot speech rate reflect the un-scripted nature of the conversations. The bot scrapes information from the relevant APIs (e.g., IMDB), leading to unique Alexa productions.
5A post-hoc model confirmed there were no interactions between Gender and the other covariates.
6More complex random effects structures resulted in singularity errors, indicating model overfit.
7We only included participants who did not have additional errors within the ± 4 turns. For example, if multiple errors occurred within four turns, we did not include those participants (n = 3).
8Posthoc models confirmed no significant interactions between Gender and the covariates.
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Keywords: vocal entrainment, socialbot, voice-activated artificially intelligent assistant, non-task oriented conversations, human-computer interaction, hyperarticulation
Citation: Cohn M, Liang K-H, Sarian M, Zellou G and Yu Z (2021) Speech Rate Adjustments in Conversations With an Amazon Alexa Socialbot. Front. Commun. 6:671429. doi: 10.3389/fcomm.2021.671429
Received: 23 February 2021; Accepted: 21 April 2021;
Published: 07 May 2021.
Edited by:Ingo Siegert, Otto von Guericke University Magdeburg, Germany
Reviewed by:Nichola Anne Lubold, Arizona State University, United States
Donna Mae Erickson, Haskins Laboratories, United States
Copyright © 2021 Cohn, Liang, Sarian, Zellou and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Michelle Cohn, firstname.lastname@example.org