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Correction ARTICLE

Front. Immunol., 13 June 2017 | https://doi.org/10.3389/fimmu.2017.00668

Corrigendum: Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes

imagePablo García-Valtanen1†, imageAlicia Martínez-López1†, imageAzucena López-Muñoz2, imageMelissa Bello-Perez1, imageRegla M. Medina-Gali1, imageMaría del Mar Ortega-Villaizán1, imageMonica Varela3, imageAntonio Figueras3, imageVíctoriano Mulero2, imageBeatriz Novoa3, imageAmparo Estepa1 and imageJulio Coll4*
  • 1Departamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH), Alicante, Spain
  • 2Facultad de Biología, Departamento de Biología Celular e Histología, Universidad de Murcia, IMIB-Arrixaca, Murcia, Spain
  • 3Instituto deInvestigaciones Marinas (IIM), Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain
  • 4Departamento de Biotecnología, Instituto Nacional Investigación y Tecnología Agraria y Alimentaria (INIA), Madrid, Spain

A corrigendum on

Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes
by García-Valtanen P, Martínez-López A, López-Muñoz A, Bello-Perez M, Medina-Gali RM, Ortega-Villaizán M, et al. Front Immunol (2017) 8:121. doi: 10.3389/fimmu.2017.00121

In the original article there were two inaccurate statements, in the introduction and method sections, which may lead to misunderstanding the way previous microarray profiles of uninfected rag1−/− zebrafish were studied by Jima et al. 2009 (ref 49 in the paper). The meaning should be clear that in previous work, rag1−/− zebrafish were compared to heterozygous rag+/− while in the present work they were compared to homozygous rag1+/+. The authors sincerely apologize for those inaccurate statements. These errors did not change the scientific conclusions of the article in any way.

The correct version of the introduction 3rd paragraph, statement on line 25 should more accurately read:

Probably, due to the difficulties encountered when breeding rag1−/− zebra fish, their gene expression profiles in response to viral infection, has yet to be compared to rag1+/+.

The correct version of the materials and methods, zebra fish (Danio rerio) section, statement on line 13 should now be more accurate as:

These difficulties may explain why few people could make experiments with them and why only comparisons of rag1−/− to heterozygous rag1+/− have been used for microarray analysis (49).

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Keywords: zebra fish rag1−/− adaptive deficient mutants, spring viremia carp viral infections, multigene families and apoptosis in resistance to viral infections, trained immunity NK/macrophages in fish, antiviral alert state

Citation: García-Valtanen P, Martínez-López A, López-Muñoz A, Bello-Perez M, Medina-Gali RM, del Mar Ortega-Villaizán M, Varela M, Figueras A, Mulero V, Novoa B, Estepa A and Coll J (2017) Corrigendum: Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes. Front. Immunol. 8:668. doi: 10.3389/fimmu.2017.00668

Received: 29 April 2017; Accepted: 23 May 2017;
Published: 13 June 2017

Edited and Reviewed by: Francesca Granucci, University of Milano-Bicocca, Italy

Copyright: © 2017 García-Valtanen, Martínez-López, López-Muñoz, Bello-Perez, Medina-Gali, del Mar Ortega-Villaizán, Varela, Figueras, Mulero, Novoa, Estepa and Coll. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Julio Coll, juliocoll@inia.es

These authors have contributed equally to this work.