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Correction ARTICLE

Front. Immunol., 07 December 2017 | https://doi.org/10.3389/fimmu.2017.01735

Corrigendum: Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand

imageJin-Hee Kim1,2†, imageJi Hyun Sim1†, imageSunkyung Lee1, imageMin A. Seol1,3,4, imageSang-Kyu Ye3,4,5,6, imageHyun Mu Shin1,3,4,6, imageEun Bong Lee6,7, imageYun Jong Lee7, imageYun Jung Choi8, imageWan-Hee Yoo8, imageJin Hyun Kim9, imageWan-Uk Kim10, imageDong-Sup Lee1,3,4,6, imageJin-Hong Kim11, imageInsoo Kang12, imageSeong Wook Kang9* and imageHang-Rae Kim1,3,4,6*
  • 1Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, South Korea
  • 2Department of Biomedical Laboratory Science, College of Health Science, Cheongju University, Cheongju, South Korea
  • 3Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea
  • 4BK21Plus Biomedical Science Project, Seoul National University College of Medicine, Seoul, South Korea
  • 5Department of Pharmacology, Seoul National University College of Medicine, Seoul, South Korea
  • 6Medical Research Institute, Seoul National University College of Medicine, Seoul, South Korea
  • 7Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
  • 8Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital, Jeonju, South Korea
  • 9Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, South Korea
  • 10Department of Internal Medicine, The Catholic University of Korea, Seoul, South Korea
  • 11Department of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, South Korea
  • 12Department of Internal Medicine, Section of Rheumatology, Yale University School of Medicine, New Haven, CT, United States

A corrigendum on

Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand
by Kim JH, Sim JH, Lee S, Seol MA, Ye SK, Shin HM, et al. Front Immunol (2017) 8:1376. doi: 10.3389/fimmu.2017.01376

In the original article, there was a mistake in the legend for Figure 2 as published. Here, the expression “SFMCs from healthy individuals” should be corrected to “SFMCs”. The correct legend appears below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.

FIGURE 2 | Interleukin (IL)-7 induced osteoclast formation in synovial fluid mononuclear cells (SFMCs) from joint fluid of rheumatoid arthritis (RA) patients. SFMCs were cultured with M-CSF (20 ng/mL), RANKL (50 ng/mL), or IL-7 (2 ng/mL) for 10 days by replacing the medium at 3-day intervals with fresh cytokines as described in Figure 1 (left panel). To determine the effect of pretreatment with IL-7, SFMCs were cultured with IL-7 (2 ng/mL) for 3 days, then treated with M-CSF (20 ng/mL), RANKL (50 ng/mL), or IL-7 (2 ng/mL) for 7 days, replacing the medium as described above (right panel). TRAP staining and enumeration were performed as described in Figure 1. Representative images (A) and quantification (B) of TRAP+ cells at days 10 and 15 are shown. Results are representative of five independent experiments with five different donors. Bars represent the mean and p values were obtained using the unpaired two-tailed Student’s t-test. (C) Peripheral blood mononuclear cells were cultured on top of dentine disks in 96-well culture plates in the above condition for 30 days. Then, surface roughness was analyzed as described in Figure 1. Results illustrate three independent experiments (n = 3). Roughness parameter and the number of pits were analyzed as described in Figure 1. The graph represents the mean ± SEM and p values were obtained using the unpaired two-tailed Student’s t-test.

The original article was updated.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Keywords: osteoclast, intereleukin-7, intereleukin-7 receptor alpha, STAT5, RANKL, monocyte

Citation: Kim J-H, Sim JH, Lee S, Seol MA, Ye S-K, Shin HM, Lee EB, Lee YJ, Choi YJ, Yoo W-H, Kim JH, Kim W-U, Lee D-S, Kim J-H, Kang I, Kang SW and Kim H-R (2017) Corrigendum: Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand. Front. Immunol. 8:1735. doi: 10.3389/fimmu.2017.01735

Received: 20 November 2017; Accepted: 23 November 2017;
Published: 07 December 2017

Edited by:

Heiko Mühl, Goethe University Frankfurt, Germany

Reviewed by:

Hans Dooms, Boston University, United States

Copyright: © 2017 Kim, Sim, Lee, Seol, Ye, Shin, Lee, Lee, Choi, Yoo, Kim, Kim, Lee, Kim, Kang, Kang and Kim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Seong Wook Kang, kangsw@cnuh.co.kr;
Hang-Rae Kim, hangrae2@snu.ac.kr

These authors have contributed equally to this work.