In the published article (31) was not cited in the article. The citation has now been inserted in Transplacental Viral Transmission, paragraph two, the corrected paragraph appears below.
“Whilst the possibility of transmitting SARS-CoV-2 from mother to fetus during pregnancy is suggested, the role of the placenta in infection with the virus has not yet been fully understood. However, evidence suggests that pathogens can overcome this barrier, infect the fetus, and even cause serious complications in newborns, such as microcephaly and ocular abnormalities (73). Such pathogens include Cytomegalovirus (CMV), herpes simplex virus (HSV), varicella-zoster virus, and Zika virus (ZIKV) (20, 74–76). It is currently unclear whether neonates who tested positive for SARS-CoV-2 have been infected with the virus from their mothers during pregnancy or have been infected during labor or after birth. (Table 1). Evidence based on infant antibody tests suggests vertical transmission of the virus may be possible. It was discovered that infants born to women infected with SARS-CoV-2 had higher immunoglobulin (Ig) G and IgM levels for SARS-CoV-2 (31, 88, 89). The presence of IgG in the fetus may indicate the transfer of this immunoglobulin from the mother to the fetus during pregnancy, but the presence of IgM indicates that the fetus has produced and secreted this immunoglobulin in response to viral infection because in contrast to IgG, IgM is unable to cross the placenta due to its higher molecular weight (88, 89).”
Additionally, in the published article Komine-Aizawa S, Takada K, Hayakawa S. Placental barrier against COVID-19. Placenta. 2020 Sep 15;99:45-49. doi: 10.1016/j.placenta.2020.07.022 was not cited. The citation has now been inserted in the Figure 3 legend as shown and the corresponding reference added to the reference list.
Figure 3

Possible mechanisms of transplacental transmission. There are several potential mechanisms involved in the virus’s vertical transmission from mother to fetus. (1) Infection caused by direct villous tree damage. (2) Infection through the maternal endothelium to the extravillous trophoblast. (3) Infection caused by maternal immune cell trafficking and transcellular transport. (4) Infection through the vagina. Adapted from (67).
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way.
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Statements
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
References
1
Komine-AizawaSTakadaKHayakawaS. Placental barrier against COVID-19. Placenta (2020) 99:45–9. doi: 10.1016/j.placenta.2020.07.022
Summary
Keywords
COVID-19, placenta, SARS-CoV-2, transplacental infection, pregnancy
Citation
Rad HS, Röhl J, Stylianou N, Allenby MC, Bazaz SR, Warkiani ME, Guimaraes FSF, Clifton VL and Kulasinghe A (2022) Corrigendum: The effects of COVID-19 on the placenta during pregnancy. Front. Immunol. 13:998406. doi: 10.3389/fimmu.2022.998406
Received
19 July 2022
Accepted
02 August 2022
Published
08 September 2022
Volume
13 - 2022
Edited and reviewed by
Veronique Demers-Mathieu, Exagen, Inc., United States
Updates
Copyright
© 2022 Rad, Röhl, Stylianou, Allenby, Bazaz, Warkiani, Guimaraes, Clifton and Kulasinghe.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Arutha Kulasinghe, arutha.kulasinghe@uq.edu.au
This article was submitted to Nutritional Immunology, a section of the journal Frontiers in Immunology
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.