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CORRECTION article

Front. Immunol., 17 February 2026

Sec. Cancer Immunity and Immunotherapy

Volume 17 - 2026 | https://doi.org/10.3389/fimmu.2026.1789896

Correction: FGA modulates immune infiltration and tumor progression via SLC7A11/xCT-mediated disulfidptosis in the tumor microenvironment of lung adenocarcinoma

    GL

    Gen Li 1

    QL

    Qiuping Li 2,3

    SY

    Sheng Yang 4

    DG

    Dongmei Guo 4

    YT

    Yanling Tao 3

    YJ

    Yan Jia 3*

  • 1. Department of Wound Reconstructive Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China

  • 2. Department of Clinical Medicine, Jining Medical University, Jining, China

  • 3. Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China

  • 4. Weishan County People’s Hospital, Jining, China

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There was a mistake in Figure 7 as published. Figure 7 was inadvertently overwritten by an incorrect image. The corrected Figure 7 appears below.

Figure 7

Panel A displays migration and invasion assays for A549 and NCI-H1299 cells with various treatments, alongside quantification bar graphs. Panel B shows wound healing assay images at zero, twenty-four, and forty-eight hours with corresponding migration area line graphs. Panel C presents cell proliferation bar graphs. Panels D and E display Western blot results for FGA and xCT protein interactions. Panel F contains immunofluorescence microscopy images of A549 cells highlighting xCT, nucleus, microtubules, and endoplasmic reticulum. Panel G includes bar graphs quantifying CD69 and CD25 expression. Panel H shows tissue microarray images with clinical information for lung and lung cancer samples stained for FGA.

Protein-protein interaction between FGA and xCT modulates progression and immune evasion in lung cancer. (A) Transwell migration and invasion assays were performed in a rescue experiment. (B) Wound healing assays were performed to detect cell migration in the rescue experiment. (C) Cell proliferation in the rescue experiment after 72h was detected by CCK8. (D) Endogenous FGA co-immunoprecipitates xCT in A549 cells. (E) Endogenous xCT co-immunoprecipitates FGA in A549 cells. (F) Immunostaining for xCT in A549 cell from the Human Protein Atlas. (G) Tumor cell FGA deficiency potentiates CD8+ T-cell activation via soluble factors in a non-contact Transwell co-culture system. (H) Immunohistochemical staining of FGA proteins in normal tissues and lung cancer from the Human Protein Atlas. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

The original version of this article has been updated.

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Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

immune infiltration, disulfidptosis, tumor microenvironment, non-small-cell lung cancer, lung adenocarcinoma

Citation

Li G, Li Q, Yang S, Guo D, Tao Y and Jia Y (2026) Correction: FGA modulates immune infiltration and tumor progression via SLC7A11/xCT-mediated disulfidptosis in the tumor microenvironment of lung adenocarcinoma. Front. Immunol. 17:1789896. doi: 10.3389/fimmu.2026.1789896

Received

17 January 2026

Revised

17 January 2026

Accepted

10 February 2026

Published

17 February 2026

Volume

17 - 2026

Edited and reviewed by

Nahum Puebla-Osorio, University of Texas MD Anderson Cancer Center, United States

Updates

Copyright

*Correspondence: Yan Jia,

†These authors have contributed equally to this work

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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