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Review ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Pharmacol. | doi: 10.3389/fphar.2019.01121

Anti-Methicillin Resistant Staphylococcus aureus (MRSA) Nanoantibiotics

Raphael Labreure1,  AJ Sona2,  Edward Turos2* and  Edward Turos2
  • 1Université Paris-Sud, France
  • 2University of South Florida, United States

Nanoparticle-based antibiotic constructs have become a popular area of investigation in the biomedical sciences. Much of this work has pertained to human diseases, largely in the cancer therapy arena. However, considerable research has also been devoted to the nanochemistry for controlling infectious diseases. Among these are due to bacterial infections, which can cause serious illnesses including death. The onset of multi-drug resistant (MDR) infections such as those caused by the human pathogen Staphylococcus aureus has created a dearth of problems such as surgical complications, persistent infections, and lack of available treatments. In this article we set out to review the primary literature on the design and development of new nanoparticle materials for the potential treatment of S. aureus infections, and areas that could be further expanded upon to make nanoparticle antibiotics a mainstay in clinical settings.

Keywords: methicillin-resistant S aureus, MRSA, Nanoparticles, Nanoantibiotics, Nanomedicines

Received: 04 Apr 2019; Accepted: 30 Aug 2019.

Copyright: © 2019 Labreure, Sona, Turos and Turos. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Prof. Edward Turos, University of South Florida, Tampa, 33620, Florida, United States, eturos@usf.edu