Frontiers in Pharmacology

Review

Published on 04 Mar 2026

The role of immune regulation in peripheral nerve regeneration: functions of inflammatory cells and cytokines

in Inflammation Pharmacology

Yongkun Zhang
Haochun Zhang
Yun Su
Min Nuo
Wenguang Wu
Haochen Jiang
Xiangjun Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1735833

186 views

Original Research

Published on 04 Mar 2026

A retrospective analysis of outpatient use of small-molecule targeted inhibitors for lymphoma across six regions of China (2016–2022)

in Pharmacology of Anti-Cancer Drugs

Bo Chen
Li-Ying Chen
Ping Chen
Chen Wang
Chang-Wei Yang
Yan Hu
Ran Wei
Liu-Cheng Li
Zhen-Ling Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1784805

Systematic Review

Published on 04 Mar 2026

Efficacy and safety of immune checkpoint inhibitors combined with chemoradiotherapy in locally advanced cervical cancer: a systematic review and meta-analysis

in Pharmacology of Anti-Cancer Drugs

Chao Xiao
Siyuan Zeng
Luying Li
Ruiqi Wang
Xue Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1766157

178 views

Original Research

Published on 04 Mar 2026

Anticoagulant-free preparation of autologous platelet-rich plasma (PRP) / fluid platelet-rich fibrin (f-PRF): a pre-clinical comparative performance study

in Integrative and Regenerative Pharmacology

Alice Assinger
Anita Pirabe
Jonas Santol
Abbas Muhammad
David Kuroki-Hasenöhrl

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1785884

Correction

Published on 04 Mar 2026

Correction: Erythropoietin mitigates diabetic nephropathy by restoring PINK1/Parkin-mediated mitophagy

in Renal Pharmacology

Xinyao Yi
Wenhui Yan
Tingli Guo
Na Liu
Zhuanzhuan Wang
Jia Shang
Xiaotong Wei
Xin Cui
Yuzhuo Sun
Shuting Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1781741

Original Research

Published on 04 Mar 2026

Investigations of the voltage-gated Ca++ channels and phosphodiesterase enzyme inhibitory-like potential explain the medicinal use of Otostegia fruticosa in diarrhea and hypermotile gut

in Gastrointestinal and Hepatic Pharmacology

Najeeb Ur Rehman
Mohd Nazam Ansari
Nasser Abdulaziz Alalaiwah
Eyad Omar Alotibi
Aman Karim
Tiegist Bahta
Khalil Y. Abujheisha
Muhammad Noman

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1790239

108 views

Review

Published on 04 Mar 2026

Epidemiological relevant effect biomarkers for thyroid hormone system related adverse outcome pathways: a literature review

in Predictive Toxicology

Maria Wielsøe
Manhai Long
Antonios K. Stratidakis
Elisavet Renieri
Dimosthenis A. Sarigiannis
Eva Cecilie Bonefeld-Jørgensen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1760820

102 views

Clinical Trial

Published on 04 Mar 2026

Esketamine-based PCIA combined with intercostal nerve block for acute pain after lobectomy: a randomized controlled trial

in Neuropharmacology

Meiyan Zhou
Yu Qi
Fan Zhou
Hui Wu
Jiao Chen
Long Wang
Liwei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1746121

Original Research

Published on 04 Mar 2026

Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity

in Pharmacology of Anti-Cancer Drugs

Wagdy M. Eldehna
Haytham O. Tawfik
Denisa Veselá
Miroslav Peřina
Ahmed T. Negmeldin
Zainab M. Elsayed
Taghreed A. Majrashi
Veronika Vojáčková
Mostafa M. Elbadawi
Moataz A. Shaldam

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1745220

359 views

Review

Published on 04 Mar 2026

AI-driven pilot platforms and computational pharmaceutics: accelerating innovation in small molecule drug development under industry 4.0 and 5.0 paradigms

in Experimental Pharmacology and Drug Discovery

Kaixin Luo
Yuhan Yang
Sadaruddin Chachar
Chenggong Zhong
Meiqi Chen
Jun Xiong
Lianyi He
Dingying Liu
Shahla Karim Baloch
Ihab Elshoura

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1681040

158 views

Original Research

Accepted on 03 Mar 2026

Prim-O-glucosylcimifugin ameliorates DSS-induced ulcerative colitis via suppressing NLRP3 inflammasome activation

in Experimental Pharmacology and Drug Discovery

Fuqian Wang
Xin Xiong
Qingfeng Ruan
Dan Zhang
Chuanqi Huang
Tingting Xie
LU CHENG

Frontiers in Pharmacology

Original Research

Accepted on 03 Mar 2026

Distribution of NUDT15*4 in Native American populations of the Brazilian Amazon and risk of intolerance to thiopurine drugs

in Pharmacogenetics and Pharmacogenomics

Guilherme Suarez-Kurtz
Anna Beatriz Ribeiro Elias
Marcelo Alex Carvaho
Alessandra Dias
Leonor Gusmão
Paulo Basta
Jamila Alessandra Perini

Frontiers in Pharmacology

Review

Accepted on 03 Mar 2026

Targeting the Gut-Immune-Brain Axis: Pharmacological Insights from Depression in Inflammatory Bowel Disease

in Inflammation Pharmacology

Júlia Leão Batista Simões
Geórgia de Carvalho Braga
Charles Elias Assmann
Margarete Dulce Bagatini

Frontiers in Pharmacology

Original Research

Accepted on 03 Mar 2026

Recombinant Human Thrombopoietin for Chronic Liver Disease-Associated Thrombocytopenia with or without Concomitant Infections: A Real-World Retrospective Study

in Gastrointestinal and Hepatic Pharmacology

Xun Wei
Li Ma
Wenbo Liu
Yamei Kuang
Xinmeng Qin
Junfeng Wei
Yi Kang

Frontiers in Pharmacology

Original Research

Accepted on 03 Mar 2026

Factors Influencing Adverse Reactions to Adrenocorticotropic Hormone Treatment in Infantile Epileptic Spasm Syndrome: a single-center retrospective study

in Drugs Outcomes Research and Policies

Yunqing Zhou
Feng Han
Yingyan Wang
Xin Zhang
Ji-Wen Wang
Kana Lin
Hao Li

Frontiers in Pharmacology

Review

Accepted on 03 Mar 2026

Alternatives to animal models in gastroenterology and hepatology research

in Gastrointestinal and Hepatic Pharmacology

Elena Gardey
Anja Rosemarie Geisler
Alina Löser
Andreas Stallmach
Anna Kipp
Stefan Lorkowski
Maria Witt-Wallert

Frontiers in Pharmacology

Original Research

Accepted on 03 Mar 2026

Modulatory role of endogenous adrenaline in propofol-related nociceptive responses in rats

in Experimental Pharmacology and Drug Discovery

Fusun Gozen
Esra Tuba Sezgin
Bulent Yavuzer
Cengiz Sarigul
Renad Mammadov
Bahadir Suleyman
Durdu Altuner
Halis Suleyman

Frontiers in Pharmacology

Editorial

Accepted on 03 Mar 2026

Enhancing Cancer Therapy: Integrating Plant-Derived Bioactives with Chemotherapy through Traditional Knowledge and Modern Advances

in Pharmacology of Anti-Cancer Drugs

Johnson O Oladele
Ebenezer Idowu Olatunbosun Ajayi
Omowumi Adewale
Olu Israel Oyewole

Frontiers in Pharmacology

Review

Accepted on 03 Mar 2026

From Microfluidics to Nanodelivery: Artificial Intelligence Reshapes Neuropharmacology Research Strategies

in Neuropharmacology

Chunbao Chen
Xue Du
Jing Yang
Yong Zeng
Hongwei Xie
Daihua Wang
Pingqiang Qi
Yijun Zeng

Frontiers in Pharmacology

Original Research

Accepted on 03 Mar 2026

Protective Role of miR-712-3p in Heatstroke-Induced Brain Injury: Involvement of Neuronal Lysosomal Function and Association with Astrocytic Exosome-enriched preparations

in Neuropharmacology

Guangli Ren
Yahong Chen
Jie Zhu
Shuhuan Li
Peishan Liang
Yiqiong Zhang

Frontiers in Pharmacology

Original Research

Accepted on 03 Mar 2026

Exploring the Therapeutic Synergy of Drug-Lifestyle Interventions in Fluorosis: A Randomized Trial on Cardiovascular Metabolic Outcomes from the China Fluorosis Cohort(CFC)

in Pharmacoepidemiology

Fuyu Tao
Yun Lu
Shaofeng Wei
Ting Hu
Rourou Wang
Chuan Ye
Feng Hong
Peng Luo

Frontiers in Pharmacology

Editorial

Accepted on 03 Mar 2026

Editorial: Novel Anti-Cancer Agents Targeting Tumour Metastasis and Stemness - Volume II

in Pharmacology of Anti-Cancer Drugs

Bo Wang
Luping Pang

Frontiers in Pharmacology

Review

Accepted on 03 Mar 2026

The Mechanisms of GLP-1 Receptor Agonists in Liver Diseases: Their Multifaceted Impact on Immune Response and Metabolic Regulation

in Translational Pharmacology

Zixuan Hu
Dianzhe Tian
Zuyi Yang
Junwei Zhang
Lei Zhang
Yiyao Xu
Xin Lu

Frontiers in Pharmacology

Original Research

Published on 03 Mar 2026

Bioequivalence study of testosterone undecanoate soft capsules in healthy postmenopausal women under fed conditions: a single-center, four-period, repeated crossover trial

in Drug Metabolism and Transport

Nanxing Li
Fengjia Zhu
Zhongyuan Zhao
Shilong Zhu
Jinlian Wu
Xu Zuo
Jinjin Shi
Xiuhui Qian
Xiaoping Zhang
Yuanyuan Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1763835

29,711 articles

articles

The role of immune regulation in peripheral nerve regeneration: functions of inflammatory cells and cytokines

A retrospective analysis of outpatient use of small-molecule targeted inhibitors for lymphoma across six regions of China (2016–2022)

Efficacy and safety of immune checkpoint inhibitors combined with chemoradiotherapy in locally advanced cervical cancer: a systematic review and meta-analysis

Anticoagulant-free preparation of autologous platelet-rich plasma (PRP) / fluid platelet-rich fibrin (f-PRF): a pre-clinical comparative performance study

Correction: Erythropoietin mitigates diabetic nephropathy by restoring PINK1/Parkin-mediated mitophagy

Investigations of the voltage-gated Ca++ channels and phosphodiesterase enzyme inhibitory-like potential explain the medicinal use of Otostegia fruticosa in diarrhea and hypermotile gut

Epidemiological relevant effect biomarkers for thyroid hormone system related adverse outcome pathways: a literature review

Esketamine-based PCIA combined with intercostal nerve block for acute pain after lobectomy: a randomized controlled trial

Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity

AI-driven pilot platforms and computational pharmaceutics: accelerating innovation in small molecule drug development under industry 4.0 and 5.0 paradigms

Prim-O-glucosylcimifugin ameliorates DSS-induced ulcerative colitis via suppressing NLRP3 inflammasome activation

Distribution of NUDT15*4 in Native American populations of the Brazilian Amazon and risk of intolerance to thiopurine drugs

Targeting the Gut-Immune-Brain Axis: Pharmacological Insights from Depression in Inflammatory Bowel Disease

Recombinant Human Thrombopoietin for Chronic Liver Disease-Associated Thrombocytopenia with or without Concomitant Infections: A Real-World Retrospective Study

Factors Influencing Adverse Reactions to Adrenocorticotropic Hormone Treatment in Infantile Epileptic Spasm Syndrome: a single-center retrospective study

Alternatives to animal models in gastroenterology and hepatology research

Modulatory role of endogenous adrenaline in propofol-related nociceptive responses in rats

Enhancing Cancer Therapy: Integrating Plant-Derived Bioactives with Chemotherapy through Traditional Knowledge and Modern Advances

From Microfluidics to Nanodelivery: Artificial Intelligence Reshapes Neuropharmacology Research Strategies

Protective Role of miR-712-3p in Heatstroke-Induced Brain Injury: Involvement of Neuronal Lysosomal Function and Association with Astrocytic Exosome-enriched preparations

Exploring the Therapeutic Synergy of Drug-Lifestyle Interventions in Fluorosis: A Randomized Trial on Cardiovascular Metabolic Outcomes from the China Fluorosis Cohort(CFC)

Editorial: Novel Anti-Cancer Agents Targeting Tumour Metastasis and Stemness - Volume II

The Mechanisms of GLP-1 Receptor Agonists in Liver Diseases: Their Multifaceted Impact on Immune Response and Metabolic Regulation

Bioequivalence study of testosterone undecanoate soft capsules in healthy postmenopausal women under fed conditions: a single-center, four-period, repeated crossover trial