Frontiers in Pharmacology

Original Research

Published on 01 Sep 2025

Resveratrol ameliorates osteogenic differentiation, calcification, and apoptosis of VSMCs through regulating JNK/Bax signaling

in Cardiovascular and Smooth Muscle Pharmacology

Menglin Hou
Hui Wang
Junmei Cheng
Xuyan Duan
Min Ren
Yong Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631039

219 views

Original Research

Published on 01 Sep 2025

Comparative assessment of antibacterial drugs used at the hospital level before and during COVID-19, according to the WHO AWaRe classification

in Pharmacoepidemiology

Aigerim A. Balapasheva
Gaziza A. Smagulova
Aigul Z. Mussina
Daniyar S. Dilmagambetov
Kalzhan Zh. Yermekbayeva
Mirsaid S. Kelimberdiev
Mariya S. Kulnazarova
Lazzat S. Balymbetova
Liliya E. Ziganshina

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642830

191 views

Original Research

Published on 01 Sep 2025

Synergistic antiallodynic effects of pregabalin and thioctic acid in a rat model of neuropathic pain

in Experimental Pharmacology and Drug Discovery

Edith Zárate
Vinicio Granados-Soto
Oscar Arias-Carrión

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675015

272 views

Original Research

Published on 01 Sep 2025

Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: evidence from retrospective study

in Drugs Outcomes Research and Policies

Matej Stuhec
Nusa Svetanic
Tomaz Vovk
Anteja Gorjan Gazdag
Zala Cuk
Borjanka Batinic

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667584

278 views

Systematic Review

Published on 01 Sep 2025

Systematic review and meta-analysis of specific external Chinese herbal medicines for post-stroke dysphagia: efficacy and clinical implications

in Ethnopharmacology

Jingwen Zhang
Xingyu Kang
Jingwen Zhao
Jiajie Niu
Siyu Chen
Shuai Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1635090

217 views

Original Research

Published on 01 Sep 2025

The prevalence of genetic variants of the Mas-related G-protein-coupled receptor X2 in patients does not explain perioperative hypersensitivity reactions to neuromuscular blocking agents

in Pharmacogenetics and Pharmacogenomics

Alicja Dziadowiec
Mateusz Kwitniewski
Peter Kopac
Hubert Rybka
Lenka Sedlackova
Adriana Srotova
Wojciech Dyga
Ana Koren
Joanna Gluck
Radoslaw Kitel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655722

318 views

Perspective

Published on 01 Sep 2025

The macrogol revolution in the treatment of chronic constipation. A short history of laxatives

in Gastrointestinal and Hepatic Pharmacology

Enrico Stefano Corazziari

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1662224

196 views

Review

Published on 01 Sep 2025

Unveiling the therapeutic potential of caudatin: Structural optimization, pharmacological mechanisms, and therapeutic implications

in Experimental Pharmacology and Drug Discovery

Guohui Shi
Linlin Ni
Xiaoni Kong
Rutong Ren
Xinyu Shi
Yang Xu
Zhizi Qu
Honglei Zhou
Xiusheng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1640365

Review

Published on 01 Sep 2025

Therapeutic potential of plant-derived natural products against drug-induced liver injury

in Experimental Pharmacology and Drug Discovery

Yan Chen
Yu-Qi Mei
Lin Hou
Ke-Jian Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652860

122 views

Review

Published on 01 Sep 2025

Efficacy and safety of antibody-drug conjugates in the treatment of advanced urological cancers: a systematic review and a meta-analysis

in Drugs Outcomes Research and Policies

Tian Liu
Xiao Xie
Yangz-Zi Ren
Zongyu Li
Maoping Cai
Yuzhong Yu
Lin Zhuo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583654

216 views

Brief Research Report

Published on 01 Sep 2025

Combining ethanol and cocaine exposure during adolescence increased cocaine reward sensitivity in adult rats as evaluated by a single exposure place preference paradigm

in Neuropharmacology

Carles Colom-Rocha
M. Julia García-Fuster

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668957

107 views

Original Research

Published on 01 Sep 2025

Exploring the potential of a thermosensitive in situ gel with Periplaneta americana extracts for efficient wound healing

in Inflammation Pharmacology

Shuai Liu
Shuohan Xu
Hang Lu
Xueyu Gong
Huaipeng Li
Xinyu Fan
Hongwei Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672818

115 views

Editorial

Published on 01 Sep 2025

Editorial: Natural products and nanotechnology: next-generation therapies for infectious diseases

in Pharmacology of Infectious Diseases

Dolores R. Serrano
Edilene Oliveira Silva
Vasundhra Bhandari

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682331

299 views

Original Research

Accepted on 31 Aug 2025

Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function

in Inflammation Pharmacology

Amy Kathryn Stark
John Sidney Penn

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608376

Original Research

Accepted on 30 Aug 2025

The Safety and Efficacy of Long-term Use of Calcitonin AnalogsCalcitonin-based Drugs in the Treatment of Osteoporosis in the Elderly: A Pharmacovigilance and RCT Meta-analysis

in Pharmacoepidemiology

Lingjie Tan
Sui Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514387

1,359 views

Review

Accepted on 30 Aug 2025

Neuroprotective Mechanisms of Buyang Huanwu Decoction in Ischemic Stroke

in Neuropharmacology

Yuanyuan Qin
Shiliang Hu
Shiman Mawen
Shanyao Pan
Yaping Huai
Guoqiang Liang
Ting Chen
Feiyan Zhao
Hongli Dong
Xuyi Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620533

1,212 views