Frontiers in Pharmacology

Review

Published on 07 Aug 2025

Global variation in antibiotic prescribing guidelines and the implications for decreasing AMR in the future

in Pharmacogenetics and Pharmacogenomics

Emmama Jamil
Zikria Saleem
Brian Godman
Matti Ullah
Afreenish Amir
Abdul Haseeb
Johanna C. Meyer
Muhammad Usman Qamar
Safa S. Almarzoky Abuhussain

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600787

414 views

Systematic Review

Published on 07 Aug 2025

Flavonoids in the treatment of Leishmania amazonensis: a review of efficacy and mechanisms

in Pharmacology of Infectious Diseases

Vinicius Lopes Lessa
Guilherme Drescher
Gustavo Gonçalves
João Carlos Baptista Lopes
Rafael Felipe da Costa Vieira
Fabiano Borges Figueiredo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642005

133 views

Correction

Published on 07 Aug 2025

Correction: Respiratory virus-induced bacterial dysregulation in pediatric airway tissue and the dual actions of Echinacea in reducing complications

in Ethnopharmacology

Selvarani Vimalanathan
Mahfuza Sreya
Ranganayaki Nandanavanam
Roland Schoop
Giuseppe Gancitano
Saba Saberi
Anna Malikovskaia
James Hudson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656368

Study Protocol

Published on 07 Aug 2025

Continuous infusion versus intermittent dosing of ceftazidime/avibactam in critically ill patients with Klebsiella pneumoniae OXA-48 or Pseudomonas aeruginosa infections: a single-center randomized open-label trial (ZAVICONT). Rationale and design

in Pharmacology of Infectious Diseases

Mirna Momčilović
Ivan Šitum
Ante Erceg
Marko Siroglavić
Mila Lovrić
Laura Nižić Nodilo
Anita Hafner
Jasmina Lovrić
Petra Turčić
Dora Fabijanović

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618987

178 views

Original Research

Published on 07 Aug 2025

Characteristic analysis of adverse reactions of finerenone: an in-depth analysis from WHO-VigiAccess

in Renal Pharmacology

Hongxuan Fan
Zhuolin Huang
Yafen Yang
Jiahui Li
Boda Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545148

122 views

Clinical Trial

Published on 07 Aug 2025

Clinicians’ experience on the effectiveness of pharmacotherapy in patients with first-episode depression: a randomized controlled trial based on pharmacogenomics

in Pharmacogenetics and Pharmacogenomics

Jie Tong
Jie Yuan
Yu Qin
Na Zhu
Tingting Zhang
Xiaochun Zhu
Yuanyuan Xu
Meilin Liu
Jie Zhang
Xirong Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626654

Review

Published on 07 Aug 2025

The role and challenges of intratumoral microbiota in colorectal cancer immunotherapy

in Pharmacogenetics and Pharmacogenomics

Miao Hao
Haiming Xu
Min Li
Dan Jiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634703

Correction

Published on 07 Aug 2025

Correction: Harnessing nanotechnology for stem-cell therapies: revolutionizing neurodegenerative disorder treatments – a state-of-the-art update

in Neuropharmacology

Neevashini Chengebroyen
Anmol Seelan
Kamal Yoonus Thajudeen
Saad Ali Alshehri
Aritra Biswas
Israrahmed Adur
Vino Sundararajan
Sajitha Lulu Sudhakaran
Harpreet Singh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1674993

236 views

Clinical Trial

Published on 07 Aug 2025

The anti-inflammatory and antioxidant effects of astaxanthin as an adjunctive therapy in community-acquired pneumonia: a randomized controlled trial

in Inflammation Pharmacology

Fatma Makram Youssef
Hayam Ateyya
Amir Eskander Hanna Samy
Eman Mohamed Elmokadem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621308

331 views

Original Research

Published on 07 Aug 2025

The pivotal regulatory role of the FEV-SLC7A11 axis in ferroptosis elucidates the anti-aging mechanism of β-sitosterol in a cross-species study

in Ethnopharmacology

Zhihan Fang
Liyao Xie
Jing Wang
Junyi Li
Yirui Pan
Lei Chen
Shuyi Cao
Qi Zhou
Shaobin Li
Chao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600489

168 views

Correction

Published on 07 Aug 2025

Correction: Novel mitophagy inducer TJ0113 alleviates pulmonary inflammation during acute lung injury

in Respiratory Pharmacology

Zhengyuan Liu
Danruo Fang
Kaijun Chen
Lingling Dong
Huaqiong Huang
Zhihua Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667879

121 views

Correction

Published on 07 Aug 2025

Correction: Reversal of ABCG2-mediated drug resistance by tinodasertib (ETC-206)

in Experimental Pharmacology and Drug Discovery

Haigan Yang
Zheshen Li
Zhuoxun Wu
Xiang Chen
Letao Bo
Harsh Patel
Bohan Zhang
Wenjun Xiong
Wei Wang
Zhe-Sheng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1648210

136 views

Correction

Published on 07 Aug 2025

Correction: Formulation of zein nanoparticles for augmenting the anti-inflammatory activity of dexketoprofen

in Experimental Pharmacology and Drug Discovery

Mahmoud A. El Hassab
Mona H. Ibrahim
Sherif S. Abdel Mageed
Abdulla M. A. Mahmoud
Zainab Sabry Othman Ahmed
Shaimaa Mosallam
Manar Adel Abdelbari
Eman F. Khaleel
Maram A. El Hasab
Asmaa Elsayyad

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658349

Original Research

Accepted on 06 Aug 2025

Systematic Bioinformatics Analysis Identifies Shikonin as a Novel mTOR Pathway Inhibitor in Triple-Negative Breast Cancer Progression

in Experimental Pharmacology and Drug Discovery

Ying Liang
Wenna Liu
Qingqing Liu
Jing-yue Yao
Dan Wu
Wenxuan Li
Zhenkai Fu
Ming-gao Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1603093

Review

Accepted on 06 Aug 2025

Regulation mechanism of curcumin mediated inflammatory pathway and its clinical application：A Review

in Ethnopharmacology

Meihua Liu
Jingyi Wang
Zhen Song
Yong Pei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642248

Editorial

Accepted on 06 Aug 2025

Editorial: Advances in Pharmacotherapy for Alcohol Use Disorder: From Mechanisms to Clinical Interventions

in Experimental Pharmacology and Drug Discovery

Regina A Mangieri
Sunil Sirohi
Ezequiel Marron Fernandez De Velasco
Seungwoo Kang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671114