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Correction ARTICLE

Front. Pharmacol., 29 May 2020 | https://doi.org/10.3389/fphar.2020.00772

Corrigendum: Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence

Yue-Hua Jiang1,2†, Ling-Yu Jiang3†, Yong-Cheng Wang3, Du-Fang Ma3 and Xiao Li3*
  • 1Central Laboratory, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
  • 2First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China
  • 3Cardiovascular Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China

A Corrigendum on
Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence

Jiang Y-H, Jiang L-Y, Wang Y-C, Ma D-F and Li X (2020). Front. Pharmacol. 11:512. doi: 10.3389/fphar.2020.00512

In the original article, there was a mistake in Figure 3 as published. The wrong image of ROS generation in the 3 μm Que+ox-LDL group was unintentionally used in Figure 3C. The fully corrected Figure 3 appears below.

FIGURE 3
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Figure 3 Effect of Quercetin on apoptosis, reactive oxygen species (ROS), and ΔΨm. Human aortic endothelial cells (HAECs) were cultured for 48 h in the presence of 50 μg/ml ox-LDL, or 50 μg/ml ox-LDL followed with different quercetin (3, 1 or 0.3 μmol/L), and untreated HAECs was used as normal control. (A) viability of HAECs was determined by MTT assay. (B) Apoptosis rate was determined by Annexin V-FITC/PI. (C) ROS generation was determined by 2',7'-dichlorofluorescin diacetate (DCFH-DA). (D) The degree of mitochondrial depolarization and ΔΨm was assayed by JC-1 staining and ΔΨm was assessed by the relative ratio of red fluorescence to green fluorescence via flow cytometer. ΔΨm reversibly changes color from green to red as the membrane potential increases (values of > 80–100 mV). *P < 0.05, vs untreated HAECs; ΔP < 0.05, vs ox-LDL; n = 3.

The authors apologize for this error that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: quercetin, endothelial cellular senescence, atherosclerosis, oxidized low-density lipoprotein, ApoE-/- mice

Citation: Jiang Y-H, Jiang L-Y, Wang Y-C, Ma D-F and Li X (2020) Corrigendum: Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence. Front. Pharmacol. 11:772. doi: 10.3389/fphar.2020.00772

Received: 29 April 2020; Accepted: 11 May 2020;
Published: 29 May 2020.

Edited and reviewed by: Nicolau Beckmann, Novartis Institutes for BioMedical Research, Switzerland

Copyright © 2020 Jiang, Jiang, Wang, Ma and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Xiao Li, lixiao617@hotmail.com

These authors have contributed equally to this work and share first authorship