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REVIEW article

Front. Pharmacol.

Sec. Gastrointestinal and Hepatic Pharmacology

Volume 16 - 2025 | doi: 10.3389/fphar.2025.1595508

The role of gallic acid in liver disease: A review of its phytochemistry, pharmacology, and safety

Provisionally accepted
Xiaohan  ZhaiXiaohan Zhai1*Peiyu  LiPeiyu Li2Yifan  SongYifan Song2Lv  LinlinLv Linlin2Wenshuo  ZhangWenshuo Zhang2Aixi  JiaAixi Jia2Deshi  DongDeshi Dong2
  • 1The First Affiliated Hospital of Dalian Medical University, dalain, China
  • 2The First Affiliated Hospital of Dalian Medical University, Dalian, China

The final, formatted version of the article will be published soon.

On behalf of my co-author, I would like to submit the original article entitled " The role of gallic acid in liver disease: A review of its phytochemistry, pharmacology, and safety", which we wish to be considered for publication in your journal. We believe the paper may be of particular interest to the readers of your journal.In this study, we investigated to analyze the available literature on GA with a focus on its mechanism of action. These findings indicated that GA can effectively reduce non-alcoholic liver injury, alcoholic liver disease, hepatic fibrosis, drug-induced liver injury, and liver cancer.

Keywords: Gallic acid (GA), Hepatoprotective effects, Liver Diseases, Mechanism, Signaling Pathways

Received: 18 Mar 2025; Accepted: 02 Jul 2025.

Copyright: © 2025 Zhai, Li, Song, Linlin, Zhang, Jia and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xiaohan Zhai, The First Affiliated Hospital of Dalian Medical University, dalain, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.