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Study Protocol ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Psychiatry | doi: 10.3389/fpsyt.2019.00729

Prediction and Understanding of Resilience in Albertan Families: Longitudinal Study of Disaster Responses (PURLS) – Protocol

  • 1Faculty of Nursing, University of Calgary, Canada
  • 2University of Calgary , Cumming School of Medicine, Hotchkiss Brain Institute, Canada
  • 3Biological Sciences Department, University of Lethbridge, Canada
  • 4Department of Neuroscience, University of Lethbridge, Canada
  • 5Faculty of Veterinary Medicine & Hotchkiss Brain Institute, University of Calgary, Canada
  • 6Department of Psychiatry, McGill University, Canada
  • 7Departments of Psychiatry and Medical Genetics, University of Alberta, Canada
  • 8Department of Oncology, University of Alberta, Canada
  • 9Child Development Centre, University of Calgary, Canada
  • 10Physiology & Pharmacology, Obstetrics & Gynaecology, Cumming School of Medicine, University of Calgary, Canada
  • 11Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Canada

Exposure to a natural disaster in childhood can have serious, long-lasting consequences, impacting physical and mental health, development and learning. Although many children experience negative effects after a disaster, the majority do not, and what differentiates these groups is not well understood. Some of the factors that influence disaster-related outcomes in the midst of adversity include parents’ mental health, the home environment, and socioeconomic status. Furthermore, genetics has also a role to play in how children respond to stressors. We had the opportunity to conduct a natural experiment of disaster recovery following the Alberta 2013 Flood. This paper presents the detailed protocol on prediction of resilience in Albertan families, and validation with cortisol data. In addition, data collection procedures, developing resiliency screening tools, candidate gene identification, genotyping, DNA methylation and genomic analyses are described to achieve the research objectives. This study produced new knowledge by using pre- and post-disaster information on children's health and development, including children's genetics and responses to stress. This information has been identified as important to governments and other organizations invested in early child development. Our comprehensive research plan will generate evidence that can be mobilized population-based approaches to improve child and family resiliency.

Keywords: stress, resiliency, Genetics, protocol, Child Development

Received: 07 May 2019; Accepted: 11 Sep 2019.

Copyright: © 2019 Kingston, Mughal, Arshad, Kovalchuk, Metz, Wynne-Edwards, King, Aitchison, Jiang, Postovit, Wajid, McDonald, Slater, Tough and Arnold. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Muhammad Arshad, University of Calgary, Faculty of Nursing, Calgary, Canada,